Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Diarra, Issa ; Nurtop, Elif ; Sangaré, Abdoul Karim ; Sagara, Issaka ; Pastorino, Boris ; ... More +
Diarra, Issa ; Nurtop, Elif ; Sangaré, Abdoul Karim ; Sagara, Issaka ; Pastorino, Boris ; Sacko, Souleymane ; Zeguimé, Amatigué ; Coulibaly, Drissa ; Fofana, Bakary ; Gallian, Pierre ; Priet, Stephane ; Drexler, Jan Felix ; Failloux, Anna-Bella ; Dabo, Abdoulaye ; Thera, Mahamadou Ali ; Djimdé, Abdoulaye ; Kouriba, Bourèma ; Cauchemez, Simon ; de Lamballerie, Xavier ; Hozé, Nathanaël ; Doumbo, Ogobara K. Less -
Description:
The circulation of Zika virus (ZIKV) in Mali has not been clearly characterized. Therefore, we conducted a serologic survey of 793 asymptomatic volunteers >15 years of age (2016), and 637 blood donors (2013) to assess the seroprevalence of ZIKV infection in 2 ecoclimatic regions of Mali, tropical savannah and warm semiarid region, using ELISA and seroneutralization assays. The overall seroprevalence was ≈12% and increased with age, with no statistical difference between male and female participants. In the warm semiarid study sites we detected immunological markers of an outbreak that occurred in the late 1990s in 18% (95% CI 13%-23%) of participants. In tropical savannah sites, we estimated a low rate of endemic transmission, with 2.5% (95% CI 2.0%-3.1%) of population infected by ZIKV annually. These data demonstrate the circulation of ZIKV in Mali and provide evidence of a previously unidentified outbreak that occurred in the late 1990s.
Subjects:
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Arbovirus Mali Mosquitoes Research Seroprevalence Vector-Borne Infections Viruses Zika Virus Zika Virus Circulation In Mali
Source:
Emerg Infect Dis. 26(5):945-952
Pubmed ID:
32310065
Pubmed Central ID:
PMC7181926
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:3cbc91425f800ed018e1c150d179822c9336d5a108c12c8405ab2133432e897d
Download URL:
https://stacks.cdc.gov/view/cdc/87672/cdc_87672_DS1.pdf
File Type:

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