Rapid Nanopore Whole-Genome Sequencing for Anthrax Emergency Preparedness

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  McLaughlin, Heather P. ; Bugrysheva, Julia V. ; Conley, Andrew B. ; Gulvik, Christopher A. ; Cherney, Blake ; Kolton, Cari B. ; Marston, Chung K. ; Saile, Elke ; Swaney, Erin ; Lonsway, David ; Gargis, Amy S. ; Kongphet-Tran, Thiphasone ; Lascols, Christine ; Michel, Pierre ; Villanueva, Julie ; Hoffmaster, Alex R. ; Gee, Jay E. ; Sue, David
• Description:
  Human anthrax cases necessitate rapid response. We completed Bacillus anthracis nanopore whole-genome sequencing in our high-containment laboratory from a human anthrax isolate hours after receipt. The de novo assembled genome showed no evidence of known antimicrobial resistance genes or introduced plasmid(s). Same-day genomic characterization enhances public health emergency response.
• Subjects:
  Anthrax Bacillus Anthracis Bacteria Bioterrorism And Preparedness Dispatch Emergency Preparedness Nanopore Rapid Nanopore Whole-Genome Sequencing For Anthrax Emergency Preparedness Whole-genome Sequencing Zoonoses
• Source:
  Emerg Infect Dis. 26(2):358-361
• Pubmed ID:
  31961318
• Pubmed Central ID:
  PMC6986837
• Document Type:
  Journal Article
• Volume:
  26
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:b5c3c1e7b31a048a7384f40d9509c4821fbb4ce8472495334ed82b043de9bf03
• Download URL:
  https://stacks.cdc.gov/view/cdc/84843/cdc_84843_DS1.pdf
• File Type:
  [PDF - 822.34 KB ]