Streptococcus suis–Associated Meningitis, Bali, Indonesia, 2014–2017

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Susilawathi, Ni Made ; Tarini, Ni Made Adi ; Fatmawati, Ni Nengah Dwi ; Mayura, Putu I.B. ; Suryapraba, Anak Agung Ayu ; Subrata, Made ; Sudewi, Anak Agung Raka ; Mahardika, Gusti Ngurah
• Description:
  Streptococcus suis is an emerging agent of zoonotic bacterial meningitis in Asia. We describe the epidemiology of S. suis cases and clinical signs and microbiological findings in persons with meningitis in Bali, Indonesia, using patient data and bacterial cultures of cerebrospinal fluid collected during 2014-2017. We conducted microbiological assays using the fully automatic VITEK 2 COMPACT system. We amplified and sequenced gene fragments of glutamate dehydrogenase and recombination/repair protein and conducted PCR serotyping to confirm some serotypes. Of 71 cases, 44 were confirmed as S. suis; 29 isolates were serotype 2. The average patient age was 48.1 years, and 89% of patients were male. Seventy-seven percent of patients with confirmed cases recovered without complications; 11% recovered with septic shock, 7% with deafness, and 2% with deafness and arthritis. The case-fatality rate was 11%. Awareness of S. suis infection risk must be increased in health promotion activities in Bali.
• Subjects:
  Bacteria Bali Human Indonesia Meningitis/encephalitis Pork Research Streptococcus Suis Streptococcus Suis–Associated Meningitis, Bali, Indonesia, 2014–2017 Swine Zoonoses

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• Source:
  Emerg Infect Dis. 25(12):2235-2242
• Pubmed ID:
  31742523
• Pubmed Central ID:
  PMC6874276
• Document Type:
  Journal Article
• Volume:
  25
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:b0e8445bd603ae4d75f848e03f4f2ecc3bfdbb87f7311ec8172d21c5217736c0
• Download URL:
  https://stacks.cdc.gov/view/cdc/83289/cdc_83289_DS1.pdf
• File Type:
  [PDF - 1016.84 KB ]