Multiple Introductions of Domestic Cat Feline Leukemia Virus in Endangered Florida Panthers1

Chiu, Elliott S.; Kraberger, Simona; Cunningham, Mark; Cusack, Lara; Roelke, Melody; VandeWoude, Sue

i

Multiple Introductions of Domestic Cat Feline Leukemia Virus in Endangered Florida Panthers1

Supporting Files

January 2019
By Chiu, Elliott S. ; Kraberger, Simona ; Cunningham, Mark ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Chiu, Elliott S. ; Kraberger, Simona ; Cunningham, Mark ; Cusack, Lara ; Roelke, Melody ; VandeWoude, Sue
Description:

The endangered Florida panther (Puma concolor coryi) had an outbreak of infection with feline leukemia virus (FeLV) in the early 2000s that resulted in the deaths of 3 animals. A vaccination campaign was instituted during 2003-2007 and no additional cases were recorded until 2010. During 2010-2016, six additional FeLV cases were documented. We characterized FeLV genomes isolated from Florida panthers from both outbreaks and compared them with full-length genomes of FeLVs isolated from contemporary Florida domestic cats. Phylogenetic analyses identified at least 2 circulating FeLV strains in panthers, which represent separate introductions from domestic cats. The original FeLV virus outbreak strain is either still circulating or another domestic cat transmission event has occurred with a closely related variant. We also report a case of a cross-species transmission event of an oncogenic FeLV recombinant (FeLV-B). Evidence of multiple FeLV strains and detection of FeLV-B indicate Florida panthers are at high risk for FeLV infection.
Subjects:

Animals Cats Disease Outbreaks Endangered Species Genome, Viral Leukemia Virus, Feline Phylogeny Puma Research Retroviridae Infections Tumor Virus Infections
Source:

Emerg Infect Dis. 25(1):92-101
Pubmed ID:

30561312
Pubmed Central ID:

PMC6302599
Document Type:

Journal Article
Funding:

F30 OD023386/OD/NIH HHS/United States ; T32 OD012201/OD/NIH HHS/United States
Place as Subject:

Florida
Location:

North America
Volume:

25
Issue:

1
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:2d9fdc7d5d086b000225b8f52aef19abff07c52006ae4d6d66f7867be41989dc
Download URL:

https://stacks.cdc.gov/view/cdc/80453/cdc_80453_DS1.pdf
File Type:

[PDF - 2.19 MB ]

File Language:

English

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