Dengue Virus IgM Serotyping by ELISA with Recombinant Mutant Envelope Proteins

Rockstroh, Alexandra; Barzon, Luisa; Kumbukgolla, Widuranga; Su, Hoang Xuan; Lizarazo, Erley; Vincenti-Gonzalez, Maria Fernanda; Tami, Adriana; Ornelas, Alice M.M.; Aguiar, Renato Santana; Cadar, Daniel; Schmidt-Chanasit, Jonas; Ulbert, Sebastian

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Dengue Virus IgM Serotyping by ELISA with Recombinant Mutant Envelope Proteins

Supporting Files Public Domain

January 17 2019
By Rockstroh, Alexandra ; Barzon, Luisa ; Kumbukgolla, Widuranga ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Rockstroh, Alexandra ; Barzon, Luisa ; Kumbukgolla, Widuranga ; Su, Hoang Xuan ; Lizarazo, Erley ; Vincenti-Gonzalez, Maria Fernanda ; Tami, Adriana ; Ornelas, Alice M.M. ; Aguiar, Renato Santana ; Cadar, Daniel ; Schmidt-Chanasit, Jonas ; Ulbert, Sebastian
Description:

We developed an IgM-based ELISA that identifies the dengue virus serotype of recent infections. Dominant serotypes were detectable in 91.1% of samples from travelers and 86.5% of samples from residents of endemic regions; 97.1% corresponded to the serotype identified by PCR. This ELISA enables more accurate reporting of epidemiologic findings.
Subjects:

Antibodies, Viral Cross Reactions Dengue Dengue Virus Endemic Diseases Enzyme-Linked Immunosorbent Assay Humans Immunoglobulin M Mutant Proteins Recombinant Proteins Serotyping Viral Envelope Proteins
Source:

Emerg Infect Dis. 25(1):112-115
Pubmed ID:

30387417
Pubmed Central ID:

PMC6302594
Document Type:

Journal Article
Genre:

Dispatch
Place as Subject:

Germany ; Europe ; Brazil ; Venezuela ; Sri Lanka ; Vietnam
Volume:

25
Issue:

1
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:eb04633968346e922744d8d9973023e1006a8b6275afbeaee4c61e8c53a22091
Download URL:

https://stacks.cdc.gov/view/cdc/80438/cdc_80438_DS1.pdf
File Type:

[PDF - 1.14 MB ]

File Language:

English

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