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Complexity of the Basic Reproduction Number (R0)
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January 2019
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Source: Emerg Infect Dis. 25(1):1-4
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Alternative Title:Emerg Infect Dis
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Description:The basic reproduction number (R|), also called the basic reproduction ratio or rate or the basic reproductive rate, is an epidemiologic metric used to describe the contagiousness or transmissibility of infectious agents. R| is affected by numerous biological, sociobehavioral, and environmental factors that govern pathogen transmission and, therefore, is usually estimated with various types of complex mathematical models, which make R| easily misrepresented, misinterpreted, and misapplied. R| is not a biological constant for a pathogen, a rate over time, or a measure of disease severity, and R| cannot be modified through vaccination campaigns. R| is rarely measured directly, and modeled R| values are dependent on model structures and assumptions. Some R| values reported in the scientific literature are likely obsolete. R| must be estimated, reported, and applied with great caution because this basic metric is far from simple.
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Pubmed ID:30560777
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Pubmed Central ID:PMC6302597
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