Asymptomatic Dengue Virus Infections, Cambodia, 2012–2013

Ly, Sowath; Fortas, Camille; Duong, Veasna; Benmarhnia, Tarik; Sakuntabhai, Anavaj; Paul, Richard; Huy, Rekol; Sorn, Sopheak; Nguon, Kunthy; Chan, Siam; Kimsan, Souv; Ong, Sivuth; Kim, Kim Srorn; Buoy, Sowathy; Voeung, Lim; Dussart, Philippe; Buchy, Philippe; Tarantola, Arnaud

i

Asymptomatic Dengue Virus Infections, Cambodia, 2012–2013

Supporting Files Public Domain

Jul 2019
By Ly, Sowath ; Fortas, Camille ; Duong, Veasna ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Ly, Sowath ; Fortas, Camille ; Duong, Veasna ; Benmarhnia, Tarik ; Sakuntabhai, Anavaj ; Paul, Richard ; Huy, Rekol ; Sorn, Sopheak ; Nguon, Kunthy ; Chan, Siam ; Kimsan, Souv ; Ong, Sivuth ; Kim, Kim Srorn ; Buoy, Sowathy ; Voeung, Lim ; Dussart, Philippe ; Buchy, Philippe ; Tarantola, Arnaud
Description:

We investigated dengue virus (DENV) and asymptomatic DENV infections in rural villages of Kampong Cham Province, Cambodia, during 2012 and 2013. We conducted perifocal investigations in and around households for 149 DENV index cases identified through hospital and village surveillance. We tested participants 0.5-30 years of age by using nonstructural 1 rapid tests and confirmed DENV infections using quantitative reverse transcription PCR or nonstructural 1-capture ELISA. We used multivariable Poisson regressions to explore links between participants' DENV infection status and household characteristics. Of 7,960 study participants, 346 (4.4%) were infected with DENV, among whom 302 (87.3%) were <15 years of age and 225 (65.0%) were <9 years of age. We identified 26 (7.5%) participants with strictly asymptomatic DENV infection at diagnosis and during follow-up. We linked symptomatic DENV infection status to familial relationships with index cases. During the 2-year study, we saw fewer asymptomatic DENV infections than expected based on the literature.
Subjects:

Aedes Aegypti Aedes Albopictus Asymptomatic Dengue Dengue Virus Epidemiology Mosquitoes Research Risk Factors Vector-borne Infections Viruses
Source:

Emerg Infect Dis. 25(7):1354-1362
Pubmed ID:

31211672
Pubmed Central ID:

PMC6590774
Document Type:

Journal Article
Place as Subject:

Cambodia
Location:

Asia
Volume:

25
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:2cf4cd897571857eede2d8e1d4a7346c4a4c33102ac23c8ff53e3ef051ec6699
Download URL:

https://stacks.cdc.gov/view/cdc/79634/cdc_79634_DS1.pdf
File Type:

[PDF - 757.67 KB ]

File Language:

English

ON THIS PAGE

Details Supporting Files

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.