i
Phylogenetic Analysis of Enterohemorrhagic Escherichia coli O157, Germany, 1987–2008
-
Apr 2010
-
-
Source: Emerg Infect Dis. 16(4):610-616.
[PDF-261.70 KB]
Details:
-
Alternative Title:Emerg Infect Dis
-
Personal Author:
-
Description:Multilocus variable number tandem repeat analysis (MLVA) is a subtyping technique for characterizing human pathogenic bacteria such as enterohemorrhagic Escherichia coli (EHEC) O157. We determined the phylogeny of 202 epidemiologically unrelated EHEC O157:H7/H- clinical isolates through 8 MLVA loci obtained in Germany during 1987-2008. Biodiversity in the loci ranged from 0.66 to 0.90. Four of 8 loci showed null alleles and a frequency < or =44.1%. These loci were distributed among 48.5% of all strains. Overall, 141 MLVA profiles were identified. Phylogenetic analysis assigned 67.3% of the strains to 19 MLVA clusters. Specific MLVA profiles with an evolutionary persistence were identified, particularly within sorbitol-fermenting EHEC O157:H-.These pathogens belonged to the same MLVA cluster. Our findings indicate successful persistence of this clone.
-
Subjects:
-
Source:
-
Document Type:
-
Place as Subject:
-
Location:
-
Volume:16
-
Issue:4
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
