Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Demma, Linda J.; McQuiston, Jennifer H.; Nicholson, William L.; Murphy, Staci M.; Marumoto, Pearl; ... More +
Demma, Linda J.; McQuiston, Jennifer H.; Nicholson, William L.; Murphy, Staci M.; Marumoto, Pearl; Sengebau-Kingzio, J. Maireng; Kuartei, Stevenson; Durand, A. Mark; Swerdlow, David L.; Less -
Description:
Scrub typhus, caused by Orientia tsutsugamushi, is a severe febrile illness transmitted to humans by trombiculid mites, which normally feed on rodents. The first known outbreak of scrub typhus in Palau occurred in 2001 to 2003 among residents of the remote southwest islands. To determine the extent of scrub typhus distribution in Palau, we tested serum samples from humans and rodents for antibodies to O. tsutsugamushi. Of 212 Palau residents surveyed in 2003, 101 (47.6%) had immunoglobulin G (IgG) antibody titers >1:64, and 56 (26.4%) had concurrent IgG and IgM antibody titers >1:512 and 1:64, respectively. Of 635 banked serum samples collected from Palau residents in 1995, 34 (5.4%) had IgG antibody titers >1:64. Sera collected from rodents (Rattus norvegicus and R. rattus) in 2003 and 2005 were tested, and 18 (28.6%) of 63 had IgG antibody titers >1:64. These findings suggest that scrub typhus is endemic in Palau.
Subject:
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Adult
Animals
Antibodies, Bacterial
Female
Humans
Immunoglobulin G
Immunoglobulin M
Male
Rats
Research
Rodent Diseases
Scrub Typhus
Seroepidemiologic Studies

Source:
Emerg Infect Dis. 12(2):290-295.;
Document Type:
Journal Article;
Place as Subject:
Palau;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:4bc292eeb19e5da4a3334d6c4462190aed1d0a0318d272cb8895dc161957b9b0
File Type:

Supporting Files

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