Symptoms, Sites, and Significance of Mycoplasma genitalium in Men Who Have Sex with Men

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Read, Tim R.H. ; Murray, Gerald L. ; Danielewski, Jennifer A. ; Fairley, Christopher K. ; Doyle, Michelle ; Worthington, Karen ; Su, Jenny ; Mokany, Elisa ; Tan, L.T. ; Lee, David ; Vodstrcil, Lenka A. ; Chow, Eric P.F. ; Garland, Suzanne M. ; Chen, Marcus Y. ; Bradshaw, Catriona S.
• Description:
  During 2016-2017, we tested asymptomatic men who have sex with men (MSM) in Melbourne, Australia, for Mycoplasma genitalium and macrolide resistance mutations in urine and anorectal swab specimens by using PCR. We compared M. genitalium detection rates for those asymptomatic men to those for MSM with proctitis and nongonococcal urethritis (NGU) over the same period. Of 1,001 asymptomatic MSM, 95 had M. genitalium; 84.2% were macrolide resistant, and 17% were co-infected with Neisseria gonorrhoeae or Chlamydia trachomatis. Rectal positivity for M. genitalium was 7.0% and urine positivity was 2.7%. M. genitalium was not more commonly detected in the rectums of MSM (n = 355, 5.6%) with symptoms of proctitis over the same period but was more commonly detected in MSM (n = 1,019, 8.1%) with NGU. M. genitalium is common and predominantly macrolide-resistant in asymptomatic MSM. M. genitalium is not associated with proctitis in this population.
• Subjects:
  Anti-Bacterial Agents Coinfection Cross-Sectional Studies Drug Resistance, Bacterial Homosexuality, Male Humans Male Mycoplasma Genitalium Mycoplasma Infections Odds Ratio Prevalence Public Health Surveillance Sexually Transmitted Diseases, Bacterial Symptom Assessment

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• Source:
  Emerg Infect Dis. 25(4):719-727
• Pubmed ID:
  30882306
• Pubmed Central ID:
  PMC6433010
• Document Type:
  Journal Article
• Place as Subject:
  Australia
• Volume:
  25
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:305c7a641a7ffc205733db5a2e202d3d6b12a23edcf4c8c9763b8aa0fe681a06
• Download URL:
  https://stacks.cdc.gov/view/cdc/77146/cdc_77146_DS1.pdf
• File Type:
  [PDF - 2.20 MB ]