Welcome to CDC stacks |
Stacks Logo
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
 
 
Help
Clear All Simple Search
Advanced Search
The National Institute of General Medical Sciences probes cellular and molecular bases of life.
  • Published Date:
    1983 Jan-Feb
  • Source:
    Public Health Rep. 98(1):40-43
  • Language:
    English
Filetype[PDF-2.00 MB]


Details:
  • Supporting Files:
    No Additional Files
You May Also Like:
  1. Public Health Reports ; v. 98 , no. 1 : cover
    Published Date:
    Jan-Feb 1983
    Source:
    Public Health Rep 98 (1)
    File Type:
    Filetype[PDF - 469.47 KB]
  2. Public Health Rep ; v. 98, no. 1 : table of contents
    Published Date:
    Jan-Feb 1983
    Source:
    Public Health Rep. 98(1)
    File Type:
    Filetype[PDF - 335.90 KB]
  3. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
    Personal Author:
    Ran, F. Ann; Hsu, Patrick D.; Lin, Chie-Yu; Gootenberg, Jonathan S.; Konermann, Silvana; Trevino, Alexandro; Scott, David A.; Inoue, Azusa; Matoba, Shogo; Zhang, Yi; Zhang, Feng;
    Published Date:
    Aug 29 2013
    Source:
    Cell. 2013; 154(6):1380-1389.
    Description:
    Targeted genome editing technologies have enabled a broad range of research and medical applications. The Cas9 nuclease from the microbial CRISPR-Cas system is targeted to specific genomic loci by a 20 nt guide sequence, which can tolerate certain mi...
    File Type:
    Filetype[PDF - 1.36 MB]
  4. DNA targeting specificity of RNA-guided Cas9 nucleases
    Personal Author:
    Hsu, Patrick D.; Scott, David A.; Weinstein, Joshua A; Ran, F. Ann; Konermann, Silvana; Agarwala, Vineeta; Li, Yinqing; Fine, Eli J.; Wu, Xuebing; Shalem, Ophir; Cradick, Thomas J.; Marraffini, Luciano A.; Bao, Gang; Zhang, Feng;
    Published Date:
    Jul 21 2013
    Source:
    Nat Biotechnol. 2013; 31(9):827-832.
    Description:
    The Streptococcus pyogenes Cas9 (SpCas9) nuclease can be efficiently targeted to genomic loci by means of single-guide RNAs (sgRNAs) to enable genome editing. Here, we characterize SpCas9 targeting specificity in human cells to inform the selection o...
    File Type:
    Filetype[PDF - 1.33 MB]
  5. Competitive Genomic Screens of Barcoded Yeast Libraries
    Personal Author:
    Smith, Andrew M.; Durbic, Tanja; Oh, Julia; Urbanus, Malene; Proctor, Michael; Heisler, Lawrence E.; Giaever, Guri; Nislow, Corey;
    Published Date:
    Aug 11 2011
    Source:
    J Vis Exp. 2011; (54).
    Description:
    By virtue of advances in next generation sequencing technologies, we have access to new genome sequences almost daily. The tempo of these advances is accelerating, promising greater depth and breadth. In light of these extraordinary advances, the nee...
    File Type:
    Filetype[PDF - 539.72 KB]