Welcome to CDC stacks | Research on alcohol metabolism among Asians and its implications for understanding causes of alcoholism. - 63387 | Public Health Reports
Stacks Logo
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
 
 
Help
Clear All Simple Search
Advanced Search
Research on alcohol metabolism among Asians and its implications for understanding causes of alcoholism.
  • Published Date:
    1989 Nov-Dec
  • Source:
    Public Health Rep. 104(6):615-620
  • Language:
    English
Filetype[PDF-1.05 MB]


Details:
  • Personal Authors:
    Suddendorf, R F
  • Keywords:
  • Pubmed ID:
    2511595
  • Pubmed Central ID:
    PMCnull
  • Description:
    Research into the causes of alcoholism is a relatively recent scientific endeavor. One area of study which could lead to better understanding of the disease is the possibility of a genetic predisposition to alcoholism. Recent work has demonstrated that people have varying complements of enzymes to metabolize alcohol. Current knowledge is examined about the influence of various ethanol metabolizing enzymes on alcohol consumption by Asians and members of other ethnic groups. The two principal enzymes involved in ethanol oxidative metabolism are alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). ADH is responsible for the metabolism of ethanol to acetaldehyde. ALDH catalyzes the conversion of acetaldehyde to acetate. The different isozymes account for the diversity of alcohol metabolism among individuals. An isozyme of ADH (beta 2 beta 2) is found more frequently in Asians than in whites, and an ALDH isozyme (ALDH2), although present in Asians, often is in an inactive form. The presence of an inactive form of ALDH2 is thought to be responsible for an increase in acetaldehyde levels in the body. Acetaldehyde is considered responsible for the facial flushing reaction often observed among Asians who have consumed alcohol. A dysphoric reaction to alcohol, producing uncomfortable sensations, is believed to be a response to deter further consumption. Although the presence of an inactive ALDH2 isozyme may serve as a deterrent to alcohol consumption, its presence does not fully explain the levels of alcohol consumption by those with the inactive isozyme. Other conditions, such as social pressure, and yet undetermined biological factors, may play a significant role in alcohol consumption.

  • Document Type:
    Journal Article
  • Collection(s):
    Public Health Reports
  • Main Document Checksum:
  • Supporting Files:
    No Additional Files
    1. Long-term secular trends in initiation of cigarette smoking among Hispanics in the United States.
      Personal Author:
      Escobedo, L G; Remington, P L; Anda, R F;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):583-587
      Description:
      Preventing the initiation of cigarette smoking plays a vital role in reducing rates of cigarette smoking. The authors investigated trends in cigarette smoking initiation among Mexican Americans, Cuban Americans, Puerto Rican Americans, compared with ...
      File Type:
      Filetype[PDF - 1.13 MB]
    2. Public Health Rep
      Published:
      Nov-Dec 1989
      File Type:
      Filetype[PDF - 594.73 KB]
    3. Improving the health of minorities.
      Personal Author:
      Mason, J O
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):523-525
      File Type:
      Filetype[PDF - 521.49 KB]
    4. Sign ordinance aimed at alcohol use by young adults in two Florida countries.
      Personal Author:
      Cleary, D
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):525-526
      File Type:
      Filetype[PDF - 324.19 KB]
    5. Development of a community cancer education program: the Forsyth County, NC cervical cancer prevention project.
      Personal Author:
      Michielutte, R; Dignan, M B; Wells, H B; Young, L D; Jackson, D S; Sharp, P C;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):542-551
      Description:
      The authors outline the development and implementation of a public health education program for cervical cancer screening among black women in Forsyth County, NC. The educational program includes distributing electronic and printed information media ...
      File Type:
      Filetype[PDF - 1.64 MB]
    6. Meeting minority health needs through special MCH projects.
      Personal Author:
      Hutchins, V; Walch, C;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):621-626
      Description:
      The maternal and child health programs of the Public Health Service have always been directed to minority populations; however, the recent surges of immigrants from Asian and Central American countries have caused the agency to appraise its efforts t...
      File Type:
      Filetype[PDF - 1.30 MB]
    7. Black-on-black homicide: Kansas City's response.
      Personal Author:
      Mitchell, M A; Daniels, S;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):605-608
      Description:
      In many metropolitan areas, homicide continues to be the scourge of black Americans despite increasing awareness of the overrepresentation of blacks among victims and perpetrators. The risk of being a homicide victim among black males is so high that...
      File Type:
      Filetype[PDF - 716.18 KB]
    8. Public Health Reports ; v. 104, no. 6 : table of contents
      Published:
      Nov-Dec 1989
      Source:
      Public Health Rep. 104(6)
      File Type:
      Filetype[PDF - 483.41 KB]
    9. An urban community-based cancer prevention screening and health education intervention in Chicago.
      Personal Author:
      Lacey, L P; Phillips, C W; Ansell, D; Whitman, S; Ebie, N; Chen, E;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):536-541
      Description:
      Most types of cancer are disproportionately present in black populations. Among all ethnic and racial groups, black people have the highest incidence of all types of cancer combined, experiencing the highest mortality and the worst survival rate. A m...
      File Type:
      Filetype[PDF - 1.20 MB]
    10. Participation rates, weight loss, and blood pressure changes among obese women in a nutrition-exercise program.
      Personal Author:
      Lasco, Richard A.; Curry, Robert H.; Dickson, V. Joann; Powers, Judy; Menes, Sandra; Merritt, Robert K.;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):640-646
      Description:
      Since 1985, a black urban community in Atlanta has planned, implemented, and evaluated a cardiovascular risk reduction project. The Community Health Assessment and Promotion Project (CHAPP) was developed to reduce the high incidence of cardiovascular...
      File Type:
      Filetype[PDF - 1.46 MB]
    11. PHS grants for minority group HIV infection education and prevention efforts.
      Personal Author:
      Bowles, J; Robinson, W A;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):552-559
      Description:
      The Office of Minority Health (OMH) was established in December 1985 in response to recommendations developed by the Secretary's Task Force on Black and Minority Health. Originally, OMH's mission emphasized six health problems identified by the Task ...
      File Type:
      Filetype[PDF - 1.71 MB]
    12. Mexican American and white American school dropouts' drug use, health status, and involvement in violence.
      Personal Author:
      Chavez, E L; Edwards, R; Oetting, E R;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):594-604
      Description:
      A group of Mexican American and white American school dropouts were compared with a control group and a group of academically at-risk students in three locations in the Southwest. The sample group consisted of school dropouts and comparison subjects ...
      File Type:
      Filetype[PDF - 2.01 MB]
    13. Reaching Hispanics with messages to prevent alcohol and other drug abuse.
      Personal Author:
      Johnson, E M; Delgado, J L;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):588-594
      Description:
      Hispanics are often labeled a "hard-to-reach" population in the context of health communications, yet there are indicators that corporate interests increasingly are reporting successes in designing advertising and promotional campaigns targeting Hisp...
      File Type:
      Filetype[PDF - 1.36 MB]
    14. Tribal differences in diabetes: prevalence among American Indians in New Mexico.
      Personal Author:
      Carter, J; Horowitz, R; Wilson, R; Sava, S; Sinnock, P; Gohdes, D;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):665-669
      Description:
      The prevalence of diagnosed diabetes among American Indians in New Mexico with varied genetic and cultural backgrounds is reported. Utilizing community-based registries, the prevalence in persons ages 35 years and older ranged from 9.8 percent among ...
      File Type:
      Filetype[PDF - 895.58 KB]
    15. Detroit's avoidable mortality project: breast cancer control for inner-city women.
      Personal Author:
      Burack, R C; Gimotty, P A; Stengle, W; Eckert, D; Warbasse, L; Moncrease, A;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):527-535
      Description:
      Mammography remains substantially under-used in low-income minority populations despite its well-established efficacy as a means of breast cancer control. The Metropolitan Detroit Avoidable Mortality Project is a 2-year controlled clinical trial of c...
      File Type:
      Filetype[PDF - 2.00 MB]
    16. Public Health Rep ; v. 104, no. 6 : Masthead
      Published:
      Nov-Dec 1989
      Source:
      Public Health Rep. 104(6)
      File Type:
      Filetype[PDF - 2.49 MB]
    17. Risk factors for suicide among Indian adolescents at a boarding school.
      Personal Author:
      Manson, Spero M.; Beals, Janette; Dick, Rhonda Wiegman; Duclos, Christine;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):609-614
      Description:
      Suicide rates among American Indians, especially adolescents, are higher than those for the general population. This paper summarizes the relevant literature on prevalence of, and risk factors for, suicide among American Indian groups, with a strong ...
      File Type:
      Filetype[PDF - 1017.20 KB]
    18. Tuberculosis: an increasing problem among minorities in the United States.
      Personal Author:
      Snider, D E; Salinas, L; Kelly, G D;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):646-653
      Description:
      Although the number of tuberculosis cases reported annually in the United States has decreased markedly during the past three and a half decades, the decrease among whites has been considerably greater than among nonwhites. As a result of this wideni...
      File Type:
      Filetype[PDF - 1.98 MB]
    19. The impact of sexually transmitted diseases on minority populations.
      Personal Author:
      Moran, J S; Aral, S O; Jenkins, W C; Peterman, T A; Alexander, E R;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):560-565
      Description:
      Sexually transmitted diseases (STD) are more prevalent among some minority populations in the United States than they are among the white majority. Primary and secondary syphilis occurs 45 times as often among non-Hispanic blacks as among non-Hispani...
      File Type:
      Filetype[PDF - 1.50 MB]
    20. Using 1990 national MCH objectives to assess health status and risk in an American Indian community.
      Personal Author:
      Campbell, Bruce C.; Kimball, Ernest H.; Helgerson, Steven D.; Alexander, Isole L.; Goldberg, Howard I.;
      Published:
      1989 Nov-Dec
      Source:
      Public Health Rep. 104(6):627-631
      Description:
      The authors used data from birth records to assess changes in health risks and health status of American Indians (AI) living in Umatilla County, OR, from 1973 to 1986. They compared the AI health risks and health status with those of other persons (n...
      File Type:
      Filetype[PDF - 1.15 MB]
You May Also Like:
  1. Improving the health of minorities.
    Personal Author:
    Mason, J O
    Published:
    1989 Nov-Dec
    Source:
    Public Health Rep. 104(6):523-525
    File Type:
    Filetype[PDF - 521.49 KB]
  2. Sign ordinance aimed at alcohol use by young adults in two Florida countries.
    Personal Author:
    Cleary, D
    Published:
    1989 Nov-Dec
    Source:
    Public Health Rep. 104(6):525-526
    File Type:
    Filetype[PDF - 324.19 KB]
  3. Public Health Reports ; v. 104, no. 6 : table of contents
    Published:
    Nov-Dec 1989
    Source:
    Public Health Rep. 104(6)
    File Type:
    Filetype[PDF - 483.41 KB]
  4. Hospital-Admitted Injury Attributable to Alcohol
    Personal Author:
    Miller, Ted R.; Spicer, Rebecca S.;
    Published:
    Oct 17 2011
    Source:
    Alcohol Clin Exp Res. 36(1):104-112.
    Description:
    Background : Primary data collection has established that alcohol causes injuries treated in the emergency department. No comparable data exist for injuries admitted to hospital. Data on the injury risks of heavy drinkers relative to other drinkers a...
    File Type:
    Filetype[PDF - 314.54 KB]
  5. Fetal alcohol spectrum disorders; competency-based curriculum development guide for medical and allied health education and practice
    Corporate Author:
    National Center on Birth Defects and Developmental Disabilities (Centers for Disease Control and Prevention). Centers for Disease Control and Prevention (U.S.). National Organization on Fetal Alcohol Syndrome.
    Published:
    2009
    Description:
    "The Fetal Alcohol Spectrum Disorders (FASD) Competency-Based Curriculum Development Guide for Medical and Allied Health Education and Practice was developed by the FASD Regional Training Centers (RTCs), the Centers for Disease Control and Prevention...
    File Type:
    Filetype[PDF - 1.88 MB]