No Plasmodium falciparum Chloroquine Resistance Transporter and Artemisinin Resistance Mutations, Haiti

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Vincent, Jeanne P. ; Komaki-Yasuda, Kanako ; Existe, Alexandre V. ; Boncy, Jacques ; Kano, Shigeyuki
• Description:
  We obtained 78 human blood samples from areas in Haiti with high transmission of malaria and found no drug resistance-associated mutations in Plasmodium falciparum chloroquine resistance transporter and Kelch 13 genes. We recommend maintaining chloroquine as the first-line drug for malaria in Haiti. Artemisinin-based therapy can be used as alternative therapy.
• Subjects:
  Adolescent Adult Aged Antimalarials Artemisinins Child Child, Preschool Chloroquine Drug Resistance Humans Infant Malaria, Falciparum Membrane Transport Proteins Middle Aged Mutation Plasmodium Falciparum Protozoan Proteins Surveys And Questionnaires Young Adult

  More +
• Source:
  Emerg Infect Dis. 24(11):2124-2126
• Pubmed ID:
  30334724
• Pubmed Central ID:
  PMC6199976
• Document Type:
  Journal Article
• Place as Subject:
  Haiti
• Volume:
  24
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:e95f21a2a8e138690e7ddc79bd4e6346f5bb485507aa23b14c018917457e9337
• Download URL:
  https://stacks.cdc.gov/view/cdc/60399/cdc_60399_DS1.pdf
• File Type:
  [PDF - 514.34 KB ]