Effects of community-based exercise in adults with severe burns: a randomized controlled trial

Details

• Alternative Title:
  Arch Phys Med Rehabil
• Personal Author:
  Voigt, Charles D. ; Foncerrada, Guillermo ; Peña, Raquel ; Guillory, Ashley N. ; Andersen, Clark R. ; Crandall, Craig G. ; Wolf, Steven E. ; Herndon, David N. ; Suman, Oscar E.
• Description:
  Objective:
  
  To investigate the efficacy of community-based exercise programs (COMBEX) in the rehabilitation of adult burn patients as compared to standard of care (SOC).
  
  Design:
  
  Randomized controlled trial, with 2:1 randomization.
  
  Setting:
  
  Assessments were performed in a hospital setting. The intervention was performed in a community setting.
  
  Participants:
  
  Adult patients with ≥ 30% total body surface area burns were randomized to participate in COMBEX (N = 31) or standard of care (SOC) (N = 14). Patient sampling was consecutive and referred.
  
  Interventions:
  
  The COMBEX program consisted of 12 weeks of exercise with a community-based trainer after hospital discharge. The SOC group did not receive exercise training.
  
  Main Outcome Measures:
  
  Change in lean body mass index, peak torque, and VO2 max from discharge to 12 weeks post discharge, presented as mean ± SE.
  
  Results:
  
  The COMBEX group showed a significant increase in VO2 max compared to SOC (COMBEX: Δ = 7.723 ± 1.522 mL/kg/min, p = 0.0006; SOC: Δ = 2.200 ± 1.150 mL/kg/min, p = 0.0765; COMBEX vs SOC, p = 0.0236). The COMBEX group exhibited a significant within group increase in lean body mass index (Δ = 1.107 ± 0.431 kg/m2, p = 0.0003; SOC: Δ = 1.323 ± 0.873 kg/m2, p = 0.2808). Both groups showed significant within group increases in peak torque (COMBEX: Δ = 35.645 ± 7.566 N m, p = 0.0003; SOC: Δ = 34.717 ± 11.029 N m, p = 0.0082). No significant differences were noted between the 2 groups for LBMI or peak torque.
  
  Conclusions:
  
  Patients who participate in a community-based exercise program show significant improvements in cardiopulmonary fitness compared to standard of care, supporting the use of COMBEX as an alternative therapy to SOC in adults with severe burns.
• Subjects:
  • Article
  • Physical Fitness
  • Torque
  • Oxygen Consumption
  • Body Composition
  • Adolescent
  • Adult
  • Body Mass Index
  • Burns
  • Cardiorespiratory Fitness
  More +
• Source:
  Arch Phys Med Rehabil. 101(1 Suppl):S36-S41
• Pubmed ID:
  29366724
• Pubmed Central ID:
  PMC6092257
• Document Type:
  Journal Article
• Funding:
  R01 GM060388/GM/NIGMS NIH HHS/United States ; R01 HD049471/HD/NICHD NIH HHS/United States ; T32 GM008256/GM/NIGMS NIH HHS/United States ; U48 DP000043/DP/NCCDPHP CDC HHS/United States
• Volume:
  101
• Download URL:
  https://stacks.cdc.gov/view/cdc/58182/cdc_58182_DS1.pdf
• File Type:
  [PDF - 177.05 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:f6c642866a5051cefde398a6e50cbb440bf868d17a545b0b298031e909114e25