Global Distribution of Human Protoparvoviruses

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Väisänen, Elina ; Mohanraj, Ushanandini ; Kinnunen, Paula M. ; Jokelainen, Pikka ; Al-Hello, Haider ; Barakat, Ali M. ; Sadeghi, Mohammadreza ; Jalilian, Farid A. ; Majlesi, Amir ; Masika, Moses ; Mwaengo, Dufton ; Anzala, Omu ; Delwart, Eric ; Vapalahti, Olli ; Hedman, Klaus ; Söderlund-Venermo, Maria
• Description:
  Development of next-generation sequencing and metagenomics has revolutionized detection of novel viruses. Among these viruses are 3 human protoparvoviruses: bufavirus, tusavirus, and cutavirus. These viruses have been detected in feces of children with diarrhea. In addition, cutavirus has been detected in skin biopsy specimens of cutaneous T-cell lymphoma patients in France and in 1 melanoma patient in Denmark. We studied seroprevalences of IgG against bufavirus, tusavirus, and cutavirus in various populations (n = 840), and found a striking geographic difference in prevalence of bufavirus IgG. Although prevalence was low in adult populations in Finland (1.9%) and the United States (3.6%), bufavirus IgG was highly prevalent in populations in Iraq (84.8%), Iran (56.1%), and Kenya (72.3%). Conversely, cutavirus IgG showed evenly low prevalences (0%-5.6%) in all cohorts, and tusavirus IgG was not detected. These results provide new insights on the global distribution and endemic areas of protoparvoviruses.
• Subjects:
  Bufavirus Cutaneous T-cell Lymphoma Cutavirus Enteric Infections Epidemiology Gastroenteritis Global Distribution Global Distribution Of Human Protoparvoviruses Human Protoparvovirus Parvoviridae Parvovirus Research Serologic Analysis Tusavirus Viruses

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• Source:
  Emerg Infect Dis. 24(7):1292-1299.
• Pubmed ID:
  29912685
• Pubmed Central ID:
  PMC6038761
• Document Type:
  Journal Article
• Volume:
  24
• Issue:
  7
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:915e39c7574e53669bb607513b01bb2c7fe3a8af41926c3c80b957c459a3a318
• Download URL:
  https://stacks.cdc.gov/view/cdc/56950/cdc_56950_DS1.pdf
• File Type:
  [PDF - 1.10 MB ]