Hepatitis E in Long-Term Travelers from the Netherlands to Subtropical and Tropical Countries, 2008–2011

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Elfrink, Floortje ; Overbosch, Femke W. ; Schinkel, Janke ; Koen, Gerrit ; Sonder, Gerard J.B.
• Description:
  Hepatitis E virus (HEV) is a common cause of acute viral hepatitis. Virus genotypes 1 and 2 infect humans in developing countries by the fecal-oral route. To assess attack rates and disease incidence for travelers, we prospectively studied 604 long-term travelers to subtropical and tropical countries. Participants donated blood samples pretravel and posttravel and kept a diary. A total of 89/604 (15%) pretravel samples were positive for HEV IgG by ELISA, suggesting previous HEV infection. Seroconversion for HEV was found for 19/515 travelers (attack rate 3.7%, incidence 1.8 cases/1,000 person-weeks). We believe there is a substantial risk for acquiring HEV infection among long-term travelers. Although HEV infection does not seem to be a major problem in this healthy cohort, hygienic measures should be stressed in all pretravel health advice, particularly for pregnant women and immunocompromised travelers who are at risk for severe disease.
• Subjects:
  Attack Rate Hepatitis E Hepatitis E In Long-Term Travelers From The Netherlands To Subtropical And Tropical Countries, 2008–2011 Hepatitis E Virus HEV Incidence Long-term Travelers Prospective Study Research Subtropical Countries The Netherlands Travel Tropical Countries Viruses

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• Source:
  Emerg Infect Dis. 24(6):1055-1060.
• Pubmed ID:
  29774856
• Pubmed Central ID:
  PMC6004834
• Document Type:
  Journal Article
• Place as Subject:
  Netherlands
• Location:
  Europe
• Volume:
  24
• Issue:
  6
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:3daff337ca5f1ef0f0ea9d27a92c9e3a372aca0dc3f3f44fc96749d130755801
• Download URL:
  https://stacks.cdc.gov/view/cdc/56315/cdc_56315_DS1.pdf
• File Type:
  [PDF - 765.02 KB ]