External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil

Fischer, Carlo; Pedroso, Celia; Mendrone, Alfredo; Bispo de Filippis, Ana Maria; Vallinoto, Antonio Carlos Rosário; Ribeiro, Bergmann Morais; Durigon, Edison Luiz; Marques, Ernesto T.A.; Campos, Gubio S.; Viana, Isabelle F.T.; Levi, José Eduardo; Scarpelli, Luciano Cesar; Nogueira, Mauricio Lacerda; Bastos, Michele de Souza; Souza, Nathalia C. Santiago; Khouri, Ricardo; Lira, Sanny M. Costa; Komninakis, Shirley Vasconcelos; Baronti, Cécile; Charrel, Rémi N.; Kümmerer, Beate M.; Drosten, Christian; Brites, Carlos; de Lamballerie, Xavier; Niedrig, Matthias; Netto, Eduardo Martins; Drexler, Jan Felix

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External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil

May 17 2018
By Fischer, Carlo ; Pedroso, Celia ; Mendrone, Alfredo ; ...
Source: Emerg Infect Dis. 24(5):888-892

[PDF-869.04 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Fischer, Carlo ; Pedroso, Celia ; Mendrone, Alfredo ; Bispo de Filippis, Ana Maria ; Vallinoto, Antonio Carlos Rosário ; ... More +

Fischer, Carlo ; Pedroso, Celia ; Mendrone, Alfredo ; Bispo de Filippis, Ana Maria ; Vallinoto, Antonio Carlos Rosário ; Ribeiro, Bergmann Morais ; Durigon, Edison Luiz ; Marques, Ernesto T.A. ; Campos, Gubio S. ; Viana, Isabelle F.T. ; Levi, José Eduardo ; Scarpelli, Luciano Cesar ; Nogueira, Mauricio Lacerda ; Bastos, Michele de Souza ; Souza, Nathalia C. Santiago ; Khouri, Ricardo ; Lira, Sanny M. Costa ; Komninakis, Shirley Vasconcelos ; Baronti, Cécile ; Charrel, Rémi N. ; Kümmerer, Beate M. ; Drosten, Christian ; Brites, Carlos ; de Lamballerie, Xavier ; Niedrig, Matthias ; Netto, Eduardo Martins ; Drexler, Jan Felix Less -
Description:

We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied significantly. Continuous quality assurance is needed to adequately estimate risk for Zika virus-associated disease and determine patient care.
Subjects:

[+]

Humans Laboratories Molecular Diagnostic Techniques Quality Control RNA, Viral Sensitivity And Specificity Viral Load Zika Virus
Source:

Emerg Infect Dis. 24(5):888-892
Pubmed ID:

29470164
Pubmed Central ID:

PMC5938781
Document Type:

Journal Article
Genre:

Dispatch
Place as Subject:

Americas ; Brazil

Americas ; Brazil Less -
Volume:

24
Issue:

5
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:7ddfd4fe4363027d22eb92b28ec3f2aef46f00537e159214c1c322acb616495d
Download URL:

https://stacks.cdc.gov/view/cdc/54031/cdc_54031_DS1.pdf
File Type:

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