External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Fischer, Carlo ; Pedroso, Celia ; Mendrone, Alfredo ; Bispo de Filippis, Ana Maria ; Vallinoto, Antonio Carlos Rosário ; Ribeiro, Bergmann Morais ; Durigon, Edison Luiz ; Marques, Ernesto T.A. ; Campos, Gubio S. ; Viana, Isabelle F.T. ; Levi, José Eduardo ; Scarpelli, Luciano Cesar ; Nogueira, Mauricio Lacerda ; Bastos, Michele de Souza ; Souza, Nathalia C. Santiago ; Khouri, Ricardo ; Lira, Sanny M. Costa ; Komninakis, Shirley Vasconcelos ; Baronti, Cécile ; Charrel, Rémi N. ; Kümmerer, Beate M. ; Drosten, Christian ; Brites, Carlos ; de Lamballerie, Xavier ; Niedrig, Matthias ; Netto, Eduardo Martins ; Drexler, Jan Felix
• Description:
  We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied significantly. Continuous quality assurance is needed to adequately estimate risk for Zika virus-associated disease and determine patient care.
• Subjects:
  Humans Laboratories Molecular Diagnostic Techniques Quality Control RNA, Viral Sensitivity And Specificity Viral Load Zika Virus
• Source:
  Emerg Infect Dis. 24(5):888-892
• Document Type:
  Journal Article
• Genre:
  Dispatch
• Place as Subject:
  Americas ; Brazil
• Volume:
  24
• Issue:
  5
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha-512:176a8c945e80f9267c97287eef3cf6e5956ac26b670975ce3ec69139c6473fb05dbc28ce3830822fd09e76198562511c373d2eaf922a096fa1883c847e2d51f6
• Download URL:
  https://stacks.cdc.gov/view/cdc/54031/cdc_54031_DS1.pdf
• File Type:
  [PDF - 869.04 KB ]