Details:

Alternative Title:
Vaccine
Personal Author:
Yue, Xin ; Black, Carla L. ; O’Halloran, Alissa ; Lu, Peng-Jun ; Williams, Walter W. ; ... More +
Yue, Xin ; Black, Carla L. ; O’Halloran, Alissa ; Lu, Peng-Jun ; Williams, Walter W. ; Nelson, Noele P. Less -
Description:
Background

Infection with hepatitis A and hepatitis B virus can increase the risk of morbidity and mortality in persons with chronic liver disease (CLD). The Advisory Committee on Immunization Practices recommends hepatitis A (HepA) and hepatitis B (HepB) vaccination for persons with CLD.

Methods

Data from the 2014 and 2015 National Health Interview Surveys (NHIS), nationally representative, in-person interview surveys of the non-institutionalized US civilian population, were used to assess self-reported HepA (≥1 and ≥2 doses) and HepB vaccination (≥1 and ≥3 doses) coverage among adults who reported a chronic or long-term liver condition. Multivariable logistic regression was used to identify factors independently associated with HepA and HepB vaccination among adults with CLD.

Results

Overall, 19.4% and 11.5% of adults aged ≥18 years with CLD reported receiving ≥1 dose and ≥2 doses of HepA vaccine, respectively, compared with 14.7% and 9.1% of adults without CLD (p<0.05 comparing those with and without CLD, ≥1dose). Age, education, geographic region, and international travel were associated with receipt of ≥2 doses HepA vaccine among adults with CLD. Overall, 35.7% and 29.1% of adults with CLD reported receiving ≥1 dose and ≥3 doses of HepB vaccine, respectively, compared with 30.2% and 24.7% of adults without CLD (p<0.05 comparing those with and without CLD, ≥1 dose). Age, education, and receipt of influenza vaccination in the past 12 months were associated with receipt of ≥3 doses HepB vaccine among adults with CLD. Among adults with CLD and ≥10 provider visits, only 13.8% and 35.3% had received ≥2 doses HepA and ≥3 doses HepB vaccine, respectively.

Conclusions

HepA and HepB vaccination among adults with CLD is suboptimal and missed opportunities to vaccinate occurred. Providers should adhere to recommendations to vaccinate persons with CLD to increase vaccination among this population.


Subject:
[+]
Article
Chronic Liver Disease
Hepatitis A Vaccination
Hepatitis B Vaccination
National Health Interview Survey

Source:
Vaccine. 36(9):1183-1189.
Pubmed ID:
29395521
Pubmed Central ID:
PMC5805590
Document Type:
Journal Article
Funding:
CC999999/ImCDC/Intramural CDC HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:0556407bda7082d7a2cc2e14faf7c4cebf1e6c09058b1a9c029df0205a23995d
File Type:

Supporting Files

• nihms934589.nxml

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