Detection of Spotted Fever Group Rickettsia DNA by Deep Sequencing

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Graham, Rikki M.A. ; Donohue, Steven ; McMahon, Jamie ; Jennison, Amy V.
• Description:
  After conventional molecular and serologic testing failed to diagnose the cause of illness, deep sequencing identified spotted fever group Rickettsia DNA in a patient's blood sample. Sequences belonged to R. honei, the causative agent of Flinders Island spotted fever. Next-generation sequencing is proving to be a useful tool for clinical diagnostics.
• Subjects:
  DNA, Bacteria Female High-Throughput Nucleotide Sequencing Humans Middle Aged Rickettsia Sequence Analysis, DNA Spotted Fever Group Rickettsiosis
• Source:
  Emerg Infect Dis. 23(11):1911-1913.
• Pubmed ID:
  29048295
• Pubmed Central ID:
  PMC5652451
• Document Type:
  Journal Article
• Place as Subject:
  Australia
• Location:
  Oceania
• Volume:
  23
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:4550b49733d98ec57e829b6795d97a5f6332ce62e77781878a4b581ba185993d
• Download URL:
  https://stacks.cdc.gov/view/cdc/49577/cdc_49577_DS1.pdf
• File Type:
  [PDF - 330.92 KB ]