Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Nathavitharana, Ruvandhi R. ; Shi, Cynthia X. ; Chindelevitch, Leonid ; Calderon, Roger ; Zhang, Zibiao ; Galea, Jerome T. ; Contreras, Carmen ; Yataco, Rosa ; Lecca, Leonid ; Becerra, Mercedes C. ; Murray, Megan B. ; Cohen, Ted
• Description:
  Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB.
• Subjects:
  Antimicrobial Resistance Bacteria Classifier Of Tandem Repeats ClassTR Dispatch Drug Susceptibility Testing MIRU-VNTR Multidrug-resistant TB Mycobacterial Interspersed Repetitive Units–variable Number Of Tandem Repeats Mycobacterium Tuberculosis Peru Polyclonal Infection Polyclonal Pulmonary TB Infections And Risk For Multidrug Resistance, Lima, Peru Strain Diversity TB Tuberculosis Tuberculosis And Other Mycobacteria

  More +
• Source:
  Emerg Infect Dis. 23(11):1887-1890.
• Pubmed ID:
  29048297
• Pubmed Central ID:
  PMC5652442
• Document Type:
  Journal Article
• Funding:
  P30 MH062294/MH/NIMH NIH HHS/United States ; T32 MH020031/MH/NIMH NIH HHS/United States ; U01 AI057786/AI/NIAID NIH HHS/United States ; U54 GM088558/GM/NIGMS NIH HHS/United States ; Wellcome Trust/United Kingdom ; P30 AI060354/AI/NIAID NIH HHS/United States
• Volume:
  23
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:538097465f8046c40aa3cadc82dea99d33e2abb420eb5ea7c8d70f0e5a66d3b0
• Download URL:
  https://stacks.cdc.gov/view/cdc/49569/cdc_49569_DS1.pdf
• File Type:
  [PDF - 812.55 KB ]