Low Retinol Binding Protein and Vitamin D Levels are Associated with Severe Outcomes in Children Hospitalized with Lower Respiratory Tract Infection and RSV or hMPV detection

Details

• Alternative Title:
  J Pediatr
• Personal Author:
  Hurwitz, Julia L. ; Jones, Bart G. ; Penkert, Rhiannon R. ; Gansebom, Shane ; Sun, Yilun ; Tang, Li ; Bramley, Anna M. ; Jain, Seema ; McCullers, Jonathan A. ; Arnold, Sandra R.
• Description:
  Retinol binding protein and vitamin D were measured in children aged <5 years hospitalized with lower respiratory tract infection and respiratory syncytial virus and/or human metapneumovirus detections. Low vitamin levels were observed in 50% of the children and were associated with significantly elevated risk of the need for intensive care unit admission and invasive mechanical ventilation.
• Subjects:
  Article Child Child, Preschool Female Hospitalization Humans Infant Intensive Care Intensive Care Units, Pediatric Male Mechanical Ventilation Metapneumovirus Paramyxoviridae Infections Paramyxovirus Pneumonia, Viral Respiration, Artificial Respiratory Infection Respiratory Syncytial Virus, Human Respiratory Syncytial Virus Infections Respiratory Tract Retinol-Binding Proteins Vitamin D Vitamin Levels

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• Source:
  J Pediatr. 187:323-327.
• Pubmed ID:
  28578159
• Pubmed Central ID:
  PMC5588918
• Document Type:
  Journal Article
• Funding:
  P30 CA021765/CA/NCI NIH HHS/United States ; U18 IP000489/IP/NCIRD CDC HHS/United States
• Volume:
  187
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:cf47f901c6956652b4ef37c291c9ac141e8fa1f2fa70ac011c72d36de38181ea
• Download URL:
  https://stacks.cdc.gov/view/cdc/48033/cdc_48033_DS1.pdf
• File Type:
  [PDF - 324.05 KB ]