Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Benzerara, Yahia ; Gallah, Salah ; Hommeril, Baptiste ; Genel, Nathalie ; Decré, Dominique ; ... More +
Benzerara, Yahia ; Gallah, Salah ; Hommeril, Baptiste ; Genel, Nathalie ; Decré, Dominique ; Rottman, Martin ; Arlet, Guillaume Less -
Description:
FosA, a glutathione S-transferase that inactivates fosfomycin, has been reported as the cause of enzymatic resistance to fosfomycin. We show that multiple lineages of FosA-producing extended spectrum β-lactamase Escherichia coli have circulated in France since 2012, potentially reducing the efficacy of fosfomycin in treating infections with antimicrobial drug-resistant gram-negative bacilli.
Subjects:
[+]
Anti-Bacterial Agents Beta-Lactamases Drug Resistance, Multiple, Bacterial Escherichia Coli Escherichia Coli Infections Foscarnet Fosfomycin Gene Expression Humans Isoenzymes Microbial Sensitivity Tests Plasmids Prevalence
Source:
Emerg Infect Dis. 23(9):1564-1567.
Pubmed ID:
28820368
Pubmed Central ID:
PMC5572872
Document Type:
Journal Article
Name as Subject:
France ; France
France ; France Less -
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:6554a308f309fb7a8d0503640ff1f14c92a76c8b42b247fbb58bf2f63273d707
Download URL:
https://stacks.cdc.gov/view/cdc/47976/cdc_47976_DS1.pdf
File Type:

Supporting Files

• 	17-0560-F.gif	gif
  	17-0560-F.jpg	jpeg
  	17-0560.nxml	bin

More +