Emergence of Plasmid-Mediated Fosfomycin-Resistance Genes among Escherichia coli Isolates, France

Benzerara, Yahia; Gallah, Salah; Hommeril, Baptiste; Genel, Nathalie; Decré, Dominique; Rottman, Martin; Arlet, Guillaume

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Emergence of Plasmid-Mediated Fosfomycin-Resistance Genes among Escherichia coli Isolates, France

Sep 2017
By Benzerara, Yahia ; Gallah, Salah ; Hommeril, Baptiste ; ...
Source: Emerg Infect Dis. 23(9):1564-1567.

[PDF-888.43 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Benzerara, Yahia ; Gallah, Salah ; Hommeril, Baptiste ; Genel, Nathalie ; Decré, Dominique ; ... More +

Benzerara, Yahia ; Gallah, Salah ; Hommeril, Baptiste ; Genel, Nathalie ; Decré, Dominique ; Rottman, Martin ; Arlet, Guillaume Less -
Description:

FosA, a glutathione S-transferase that inactivates fosfomycin, has been reported as the cause of enzymatic resistance to fosfomycin. We show that multiple lineages of FosA-producing extended spectrum β-lactamase Escherichia coli have circulated in France since 2012, potentially reducing the efficacy of fosfomycin in treating infections with antimicrobial drug-resistant gram-negative bacilli.
Subjects:

[+]

Anti-Bacterial Agents Beta-Lactamases Drug Resistance, Multiple, Bacterial Escherichia Coli Escherichia Coli Infections Foscarnet Fosfomycin Gene Expression Humans Isoenzymes Microbial Sensitivity Tests Plasmids Prevalence
Source:

Emerg Infect Dis. 23(9):1564-1567.
Pubmed ID:

28820368
Pubmed Central ID:

PMC5572872
Document Type:

Journal Article
Name as Subject:

France ; France

France ; France Less -
Volume:

23
Issue:

9
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:6554a308f309fb7a8d0503640ff1f14c92a76c8b42b247fbb58bf2f63273d707
Download URL:

https://stacks.cdc.gov/view/cdc/47976/cdc_47976_DS1.pdf
File Type:

	17-0560-F.gif	gif
	17-0560-F.jpg	jpeg
	17-0560.nxml	bin

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