Evaluation of 5 Commercially Available Zika Virus Immunoassays

Safronetz, David; Sloan, Angela; Stein, Derek R.; Mendoza, Emelissa; Barairo, Nicole; Ranadheera, Charlene; Scharikow, Leanne; Holloway, Kimberly; Robinson, Alyssia; Traykova-Andonova, Maya; Makowski, Kai; Dimitrova, Kristina; Giles, Elizabeth; Hiebert, Joanne; Mogk, Rhonda; Beddome, Sharla; Drebot, Michael

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Evaluation of 5 Commercially Available Zika Virus Immunoassays

Sep 17 2017
By Safronetz, David ; Sloan, Angela ; Stein, Derek R. ; ...
Source: Emerg Infect Dis. 23(9):1577-1580.

[PDF-708.79 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Safronetz, David ; Sloan, Angela ; Stein, Derek R. ; Mendoza, Emelissa ; Barairo, Nicole ; ... More +

Safronetz, David ; Sloan, Angela ; Stein, Derek R. ; Mendoza, Emelissa ; Barairo, Nicole ; Ranadheera, Charlene ; Scharikow, Leanne ; Holloway, Kimberly ; Robinson, Alyssia ; Traykova-Andonova, Maya ; Makowski, Kai ; Dimitrova, Kristina ; Giles, Elizabeth ; Hiebert, Joanne ; Mogk, Rhonda ; Beddome, Sharla ; Drebot, Michael Less -
Description:

Because of the global spread of Zika virus, accurate and high-throughput diagnostic immunoassays are needed. We compared the sensitivity and specificity of 5 commercially available Zika virus serologic assays to the recommended protocol of Zika virus IgM-capture ELISA and plaque-reduction neutralization tests. Most commercial immunoassays showed low sensitivity, which can be increased.
Subjects:

[+]

Antibodies, Viral Enzyme-Linked Immunosorbent Assay Humans Immunoassay Immunoglobulin G Immunoglobulin M Neutralization Tests Sensitivity And Specificity Zika Virus Zika Virus Infection
Source:

Emerg Infect Dis. 23(9):1577-1580.
Pubmed ID:

28665268
Pubmed Central ID:

PMC5572859
Document Type:

Journal Article
Place as Subject:

Canada
Location:

North America
Volume:

23
Issue:

9
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:6fe87d8a66020523fbf9e84e3793ef926fa83bb0c0f1062a958d5e325d951ac3
Download URL:

https://stacks.cdc.gov/view/cdc/47959/cdc_47959_DS1.pdf
File Type:

16-2043.nxml

bin

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