Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Herbst, Allen ; Velásquez, Camilo Duque ; Triscott, Elizabeth ; Aiken, Judd M. ; McKenzie, Debbie
Herbst, Allen ; Velásquez, Camilo Duque ; Triscott, Elizabeth ; Aiken, Judd M. ; McKenzie, Debbie Less -
Description:
Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95(+), into mice resulted in infection. Thus, emergent CWD prion strains may have higher zoonotic potential than common strains.
Subject:
[+]
Animals
Cricetinae
Deer
Host Specificity
Humans
Mice
Prions
Protein Conformation, Alpha-Helical
Protein Conformation, Beta-Strand
Protein Stability
Species Specificity
Wasting Disease, Chronic

Source:
Emerg Infect Dis. 23(9):1598-1600.
Pubmed ID:
28820384
Pubmed Central ID:
PMC5572867
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:8df0d043553410df9ec01128e948baba03696fdc24c7ec5815102ea89cd6d0dd
File Type:

Supporting Files

• 	16-1474-Techapp-s1.pdf	pdf
  	16-1474.nxml	bin

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