Prevalence of Yersinia enterocolitica Bioserotype 3/O:3 among Children with Diarrhea, China, 2010–2015

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Duan, Ran ; Liang, Junrong ; Zhang, Jing ; Chen, Yuhuang ; Wang, Jing ; Tong, Jing ; Guo, Bangcheng ; Hu, Wanfu ; Wang, Mingliu ; Zhao, Jiayong ; Liu, Chang ; Hao, Huijing ; Wang, Xin ; Jing, Huaiqi
• Description:
  Yersinia enterocolitica is thought to not significantly contribute to diarrheal disease in China, but evidence substantiating this claim is limited. We determined the prevalence of Y. enterocolitica infection and strain types present among children <5 years of age with diarrhea in China. The overall prevalence of pathogenic isolates was 0.59%. Prevalence of pathogenic bioserotype 3/O:3 varied geographically. In this population, the presence of fecal leukocytes was a characteristic of Y. enterocolitica infection and should be used as an indication for microbiological diagnostic testing, rather than for the diagnosis of bacillary dysentery. In contrast with Y. enterocolitica isolates from adults, which were primarily biotype 1A, isolates from children were primarily bioserotype 3/O:3. Most pathogenic isolates from children shared pulsed-field gel electrophoresis patterns with isolates from pigs and dogs, suggesting a possible link between isolates from animals and infections in children. Our findings underscore the need for improved diagnostics for this underestimated pathogen.
• Subjects:
  Adult Animals Child, Preschool Diagnosis, Differential Diarrhea Dogs Dysentery, Bacillary Electrophoresis, Gel, Pulsed-Field Feces Female Humans Infant Infant, Newborn Leukocytes Male Prevalence Research Serogroup Swine Yersinia Infections

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• Source:
  Emerg Infect Dis. 23(9):1502-1509.
• Pubmed ID:
  28820132
• Pubmed Central ID:
  PMC5572862
• Document Type:
  Journal Article
• Place as Subject:
  China
• Location:
  Asia
• Volume:
  23
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:cab8105fe9b9ad3e25128d00a14423da5df119804049dac4e2b450553e8da667
• Download URL:
  https://stacks.cdc.gov/view/cdc/47946/cdc_47946_DS1.pdf
• File Type:
  [PDF - 1.89 MB ]