Postmortem Findings for 7 Neonates with Congenital Zika Virus Infection

Sousa, Anastácio Q.; Cavalcante, Diane I.M.; Franco, Luciano M.; Araújo, Fernanda M.C.; Sousa, Emília T.; Valença-Junior, José Telmo; Rolim, Dionne B.; Melo, Maria E.L.; Sindeaux, Pedro D.T.; Araújo, Marialva T.F.; Pearson, Richard D.; Wilson, Mary E.; Pompeu, Margarida M.L.

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Postmortem Findings for 7 Neonates with Congenital Zika Virus Infection

Supporting Files Public Domain

Jul 15 2017
By Sousa, Anastácio Q. ; Cavalcante, Diane I.M. ; Franco, Luciano M. ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Sousa, Anastácio Q. ; Cavalcante, Diane I.M. ; Franco, Luciano M. ; Araújo, Fernanda M.C. ; Sousa, Emília T. ; Valença-Junior, José Telmo ; Rolim, Dionne B. ; Melo, Maria E.L. ; Sindeaux, Pedro D.T. ; Araújo, Marialva T.F. ; Pearson, Richard D. ; Wilson, Mary E. ; Pompeu, Margarida M.L.
Description:

Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neurotropism and multiple organ infection.
Subjects:

Autopsy Brain Dispatch Female Humans Infant, Newborn Microcephaly Phenotype Pregnancy Pregnancy Complications, Infectious Zika Virus Zika Virus Infection
Source:

Emerg Infect Dis. 23(7):1164-1167.
Pubmed ID:

28459414
Pubmed Central ID:

PMC5512501
Document Type:

Journal Article
Place as Subject:

Brazil
Volume:

23
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:cf59140663e71b165909f50ae1016baa23337cfa643665f0e510aa60b0e82dfd
Download URL:

https://stacks.cdc.gov/view/cdc/46764/cdc_46764_DS1.pdf
File Type:

[PDF - 2.66 MB ]

File Language:

English

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