A cross-sectional analysis of radiographic ankle osteoarthritis frequency and associated factors: The Johnston County Osteoarthritis Project

Details

• Alternative Title:
  J Rheumatol
• Personal Author:
  Lateef, Shahmeer ; Golightly, Yvonne M. ; Renner, Jordan B. ; Jordan, Joanne M. ; Nelson, Amanda E.
• Description:
  Objective ; As there are no epidemiologic data regarding the frequency of ankle OA in a general population, we sought to explore this disabling condition in a large, well-characterized community-based cohort of older individuals. ; Methods ; Cross-sectional data, including ankle radiographs, were from the most recent data collection (2013–5) of the Johnston County OA Project. Radiographic ankle OA (rAOA) was defined as a Kellgren-Lawrence Grade (KLG) of ≥ 2 on weight-bearing lateral and mortise radiographs. The presence of pain, aching, or stiffness in the ankles as well as history of ankle injury (limiting ability to walk for at least 2 days) were assessed. Chi-square statistics (categorical variables) and t-tests (continuous variables) were used to compare all participant characteristics by rAOA status. Joint-based logistic regression models with generalized estimating equations were used to examine associations of rAOA and covariates of interest (age, BMI, sex, race, ankle symptoms, and injury history). ; Results ; Of 864 participants with available data, 68% were women, 34% were African American, with a mean age of 72 years and BMI of 31 kg/m2. Nearly 7% of this sample had rAOA. Increasing age, high BMI, history of ankle injury, and presence of ankle symptoms were all independently associated with greater odds of having rAOA; no significant differences were seen by sex or race. ; Conclusions ; The frequency of rAOA was higher than estimates generally quoted in the literature. While injury was an important contributor, other factors such as age, BMI, and symptoms, were also significantly associated with rAOA.
• Subjects:
  • Aged
  • Ankle Joint
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Osteoarthritis
  • Radiography
• Source:
  J Rheumatol. 44(4):499-504.
• Pubmed ID:
  28202744
• Pubmed Central ID:
  PMC5468490
• Document Type:
  Journal Article
• Funding:
  R01 AR067743/AR/NIAMS NIH HHS/United States ; U01 DP006266/DP/NCCDPHP CDC HHS/United States ; K23 AR061406/AR/NIAMS NIH HHS/United States ; P60 AR064166/AR/NIAMS NIH HHS/United States ; U01 DP003206/DP/NCCDPHP CDC HHS/United States
• Volume:
  44
• Issue:
  4
• Download URL:
  https://stacks.cdc.gov/view/cdc/46246/cdc_46246_DS1.pdf
• File Type:
  [PDF - 235.07 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:2a6eba03f2b43c56fe40df2e930d7b387a0c4b885817972af7c4b6910387d751