Development of Medical Countermeasures to Middle East Respiratory Syndrome Coronavirus

Uyeki, Timothy M.; Erlandson, Karl J.; Korch, George; O’Hara, Michael; Wathen, Michael; Hu-Primmer, Jean; Hojvat, Sally; Stemmy, Erik J.; Donabedian, Armen

i

Development of Medical Countermeasures to Middle East Respiratory Syndrome Coronavirus

Supporting Files Public Domain

July 15 2016
By Uyeki, Timothy M. ; Erlandson, Karl J. ; Korch, George ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Uyeki, Timothy M. ; Erlandson, Karl J. ; Korch, George ; O’Hara, Michael ; Wathen, Michael ; Hu-Primmer, Jean ; Hojvat, Sally ; Stemmy, Erik J. ; Donabedian, Armen
Description:

Preclinical development of and research on potential Middle East respiratory syndrome coronavirus (MERS-CoV) medical countermeasures remain preliminary; advancements are needed before most countermeasures are ready to be tested in human clinical trials. Research priorities include standardization of animal models and virus stocks for studying disease pathogenesis and efficacy of medical countermeasures; development of MERS-CoV diagnostics; improved access to nonhuman primates to support preclinical research; studies to better understand and control MERS-CoV disease, including vaccination studies in camels; and development of a standardized clinical trial protocol. Partnering with clinical trial networks in affected countries to evaluate safety and efficacy of investigational therapeutics will strengthen efforts to identify successful medical countermeasures.
Subjects:

Animal Models Animals Antibodies Antivirals Camelus Coronavirus Infections Development Of Medical Countermeasures To Middle East Respiratory Syndrome Coronavirus Diagnostics Disease Models, Animal Humans Medical Countermeasures MERS-CoV Monoclonal Non-human Primates Nonhuman Primates Online Report Polyclonal Respiratory Infections Therapeutics Vaccines Viral Vaccines Viruses
Source:

Emerg Infect Dis. 22(7)
Pubmed ID:

27191188
Pubmed Central ID:

PMC4918159
Document Type:

Journal Article
Volume:

22
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:51f7d6de40c9b663761b08a270435289a43b49175e76f82985adf308e2719cec
Download URL:

https://stacks.cdc.gov/view/cdc/45441/cdc_45441_DS1.pdf
File Type:

[PDF - 1.46 MB ]

16-0022.nxml

Download xml

File Language:

English

ON THIS PAGE

Details Supporting Files

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.