i
Pulmonary Nontuberculous Mycobacteria–Associated Deaths, Ontario, Canada, 2001–2013
-
Mar 2017
-
-
Source: Emerg Infect Dis. 23(3):468-476.
[PDF-601.47 KB]
Details:
-
Alternative Title:Emerg Infect Dis
-
Personal Author:
-
Description:Survival implications of nontuberculous mycobacterial pulmonary disease (NTM-PD) and NTM pulmonary isolation without disease (NTM-PI) are unclear. To study deaths associated with NTM-PD and NTM-PI and differences in survival between them, we conducted a population-based cohort study of persons with microbiologically defined NTM-PD or NTM-PI diagnosed during 2001-2013 in Ontario, Canada. We used propensity score matching and Cox proportional hazards models to compare survival. Among 9,681 NTM-PD patients and 10,936 NTM-PI patients, 87% and 91%, respectively, were successfully matched with unexposed controls. Both NTM-PD and NTM-PI were associated with higher rates of death for all species combined and for most individual species. Compared with NTM-PI, NTM-PD was associated with higher death rates for all species combined, Mycobacterium avium complex, and M. xenopi. NTM-PD and NTM-PI were significantly associated with death, NTM-PD more so than NTM-PI.
-
Subjects:
-
Source:
-
Pubmed ID:28221106
-
Pubmed Central ID:PMC5382758
-
Document Type:
-
Place as Subject:
-
Location:
-
Volume:23
-
Issue:3
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
