Risk Factors for Disseminated Coccidioidomycosis, United States

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Odio, Camila D. ; Marciano, Beatriz E. ; Galgiani, John N. ; Holland, Steven M.
• Description:
  Of 150,000 new coccidioidomycosis infections that occur annually in the United States, ≈1% disseminate; one third of those cases are fatal. Immunocompromised hosts have higher rates of dissemination. We identified 8 patients with disseminated coccidioidomycosis who had defects in the interleukin-12/interferon-γ and STAT3 axes, indicating that these are critical host defense pathways.
• Subjects:
  Cme Coccidioides Coccidioidomycosis Dispatch Female Genetic Predisposition To Disease Genomics / Methods Host-Pathogen Interactions Humans Immunocompromised Host Male Prognosis Risk Factors Sex Factors

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• Source:
  Emerg Infect Dis. 23(2):308-311.
• Pubmed ID:
  28098554
• Pubmed Central ID:
  PMC5324825
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Location:
  North America
• Volume:
  23
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:73cc13013038be0558e6e7765f616dc299eb53d2b127a2b13deea89e4e777754
• Download URL:
  https://stacks.cdc.gov/view/cdc/44361/cdc_44361_DS1.pdf
• File Type:
  [PDF - 463.57 KB ]