Welcome to CDC stacks |
Stacks Logo
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
 
 
Help
Clear All Simple Search
Advanced Search
A newly emerged swine origin A(H3N2)v influenza virus dampens host antiviral immunity but induces potent inflammasome activation
  • Published Date:
    Jun 11 2015
  • Source:
    J Infect Dis. 212(12):1923-1929.
Filetype[PDF-1.36 MB]


Details:
No Related Documents.
You May Also Like:
  1. Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37
    Personal Author:
    Barlow, Peter G.; Svoboda, Pavel; Mackellar, Annie; Nash, Anthony A.; York, Ian A.; Pohl, Jan; Davidson, Donald J.; Donis, Ruben O.;
    Published Date:
    Oct 21 2011
    Source:
    PLoS One. 2011; 6(10).
    Description:
    The extensive world-wide morbidity and mortality caused by influenza A viruses highlights the need for new insights into the host immune response and novel treatment approaches. Cationic Host Defense Peptides (CHDP, also known as antimicrobial peptid...
    File Type:
    Filetype[PDF - 458.75 KB]
  2. 5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication
    Personal Author:
    Ranjan, Priya; Jayashankar, Lakshmi; Deyde, Varough; Zeng, Hui; Davis, William G; Pearce, Melissa B.; Bowzard, John B.; Hoelscher, Mary A; Jeisy-Scott, Victoria; Wiens, Mayim E.; Gangappa, Shivaprakash; Gubareva, Larisa; García-Sastre, Adolfo; Katz, Jacqueline M..; Tumpey, Terrence M; Fujita, Takashi; Sambhara, Suryaprakash;
    Published Date:
    May 21 2010
    Source:
    Virol J. 2010; 7:102.
    Description:
    BackgroundEmergence of drug-resistant strains of influenza viruses, including avian H5N1 with pandemic potential, 1918 and 2009 A/H1N1 pandemic viruses to currently used antiviral agents, neuraminidase inhibitors and M2 Ion channel blockers, undersco...
    File Type:
    Filetype[PDF - 1.03 MB]
  3. Virulent PB1-F2 residues: effects on fitness of H1N1 influenza A virus in mice and changes during evolution of human influenza A viruses
    Personal Author:
    Alymova, Irina V.; McCullers, Jonathan A.; Kamal, Ram P.; Vogel, Peter; Green, Amanda M.; Gansebom, Shane; York, Ian A.;
    Published Date:
    May 10 2018
    Source:
    Sci Rep. 8.
    Description:
    Specific residues of influenza A virus (IAV) PB1-F2 proteins may enhance inflammation or cytotoxicity. In a series of studies, we evaluated the function of these virulence-associated residues in the context of different IAV subtypes in mice. Here, we...
    File Type:
    Filetype[PDF - 3.94 MB]
  4. The Inflammasome in Host Defense
    Personal Author:
    Chen, Gang; Pedra, Joao H.F.;
    Published Date:
    Dec 28 2009
    Source:
    Sensors (Basel). 2010; 10(1):97-111.
    Description:
    Nod-like receptors have emerged as an important family of sensors in host defense. These receptors are expressed in macrophages, dendritic cells and monocytes and play an important role in microbial immunity. Some Nod-like receptors form the inflamma...
    File Type:
    Filetype[PDF - 718.95 KB]
  5. Influenza virus N-linked glycosylation and innate immunity
    Personal Author:
    York, Ian A.; Stevens, James; Alymova, Irina V.;
    Published Date:
    January 08 2019
    Source:
    Biosci Rep. 2018; 39(1)
    Description:
    Influenza viruses cause seasonal epidemics and sporadic pandemics in humans. The virus's ability to change its antigenic nature through mutation and recombination, and the difficulty in developing highly effective universal vaccines against it, make ...
    File Type:
    Filetype[PDF - 1.08 MB]