Complete Genomic Sequence of Bacteriophage Felix O1†

Details

• Alternative Title:
  Viruses
• Personal Author:
  Whichard, Jean M. ; Weigt, Lee A. ; Borris, Douglas J. ; Li, Ling Ling ; Zhang, Qing ; Kapur, Vivek ; Pierson, F. William ; Lingohr, Erika J. ; She, Yi-Min ; Kropinski, Andrew M. ; Sriranganathan, Nammalwar
• Description:
  Bacteriophage O1 is a Myoviridae A1 group member used historically for identifying Salmonella. Sequencing revealed a single, linear, 86,155-base-pair genome with 39% average G+C content, 131 open reading frames, and 22 tRNAs. Closest protein homologs occur in Erwinia amylovora phage φEa21-4 and Escherichia coli phage wV8. Proteomic analysis indentified structural proteins: Gp23, Gp36 (major tail protein), Gp49, Gp53, Gp54, Gp55, Gp57, Gp58 (major capsid protein), Gp59, Gp63, Gp64, Gp67, Gp68, Gp69, Gp73, Gp74 and Gp77 (tail fiber). Based on phage-host codon differences, 7 tRNAs could affect translation rate during infection. Introns, holin-lysin cassettes, bacterial toxin homologs and host RNA polymerase-modifying genes were absent.
• Subjects:
  Article Bacteriophage Bioinformatics DNA Sequence Felix O1 Myoviridae Salmonella
• Source:
  Viruses. 2010; 2(3):710-730.
• Document Type:
  Journal Article
• Volume:
  2
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:4408912012130f195b7162e332f99d1b54194e2468f92a7c4f6183bfb60f6d0f
• Download URL:
  https://stacks.cdc.gov/view/cdc/4384/cdc_4384_DS1.pdf
• File Type:
  [PDF - 501.91 KB ]