Sequence Analysis of Toxin Gene–Bearing Corynebacterium diphtheriae Strains, Australia

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Doyle, Christine J. ; Mazins, Adam ; Graham, Rikki M.A. ; Fang, Ning-Xia ; Smith, Helen V. ; Jennison, Amy V.
• Description:
  By conducting a molecular characterization of Corynebacterium diphtheriae strains in Australia, we identified novel sequences, nonfunctional toxin genes, and 5 recent cases of toxigenic cutaneous diphtheria. These findings highlight the importance of extrapharyngeal infections for toxin gene-bearing (functional or not) and non-toxin gene-bearing C. diphtheriae strains. Continued surveillance is recommended.
• Subjects:
  Corynebacterium Diphtheriae Diphtheria Diphtheria Toxin Diphtheria Toxoid Epidemiological Monitoring Genes, Bacterial Humans Lower Extremity Mass Vaccination Mutation Pharynx Skin

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• Source:
  Emerg Infect Dis. 23(1):105-107.
• Pubmed ID:
  27983494
• Pubmed Central ID:
  PMC5176206
• Document Type:
  Journal Article
• Place as Subject:
  Australia
• Volume:
  23
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:2edf8b6f0c491bc1a5573b3a88221a401ef9dbcf5d115d5339fae14b2e8a5ca6
• Download URL:
  https://stacks.cdc.gov/view/cdc/43520/cdc_43520_DS1.pdf
• File Type:
  [PDF - 321.14 KB ]