Ambulatory Pediatric Surveillance of Hand, Foot and Mouth Disease as Signal of an Outbreak of Coxsackievirus A6 Infections, France, 2014–2015

Mirand, Audrey; le Sage, François Vié; Pereira, Bruno; Cohen, Robert; Levy, Corinne; Archimbaud, Christine; Peigue-Lafeuille, Hélène; Bailly, Jean-Luc; Henquell, Cécile

doi:10.3201/eid2211.160590

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Ambulatory Pediatric Surveillance of Hand, Foot and Mouth Disease as Signal of an Outbreak of Coxsackievirus A6 Infections, France, 2014–2015

Published Date:

Nov 2016

Publisher's site:

http://dx.doi.org/10.3201/eid2211.160590 New Site Icon

Source:

Emerg Infect Dis. 22(11):1884-1893.

[PDF-2.49 MB]

Details:

Personal Authors:

Mirand, Audrey ; le Sage, François Vié ; Pereira, Bruno ; Cohen, Robert ; Levy, Corinne ; ... More ▼

Keywords:

[+]

Pubmed ID:

27767012

Pubmed Central ID:

PMC5088007

Description:

The clinical impact of enteroviruses associated with hand, foot and mouth disease (HFMD) is unknown outside Asia, and the prevalence of enterovirus A71 (EV-A71) in particular might be underestimated. To investigate the prevalence of enterovirus serotypes and the clinical presentations associated with HFMD in France, we conducted prospective ambulatory clinic-based surveillance of children during April 2014-March 2015. Throat or buccal swabs were collected from children with HFMD and tested for the enterovirus genome. Physical examinations were recorded on a standardized form. An enterovirus infection was detected in 523 (79.3%) of 659 children tested. Two epidemic waves occurred, dominated by coxsackievirus (CV) A6, which was detected in 53.9% of enterovirus-infected children. CV-A6 was more frequently related to atypical HFMD manifestations (eruptions extended to limbs and face). Early awareness and documentation of HFMD outbreaks can be achieved by syndromic surveillance of HFMD by ambulatory pediatricians and rapid enterovirus testing and genotyping.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Main Document Checksum:

[+]

Supporting Files:

	16-0590-Techapp-s1.pdf	application/pdf
	16-0590.nxml	application/octet-stream
	16-0590-F1.gif	image/gif
	16-0590-F1.jpg	image/jpeg
	16-0590-F2.gif	image/gif
	16-0590-F2.jpg	image/jpeg
	16-0590-F3.gif	image/gif
	16-0590-F3.jpg	image/jpeg
	16-0590-F4.gif	image/gif
	16-0590-F4.jpg	image/jpeg

No Related Documents.

You May Also Like:

Emerging Coxsackievirus A6 Causing Hand, Foot and Mouth Disease, Vietnam

Personal Author:

Anh, Nguyen To; Nhu, Le Nguyen Truc; Van, Hoang Minh Tu; Hong, Nguyen Thi Thu; Thanh, Tran Tan; Hang, Vu Thi Ty; Ny, Nguyen Thi Han; Nguyet, Lam Anh; Phuong, Tran Thi Lan; Nhan, Le Nguyen Thanh; Hung, Nguyen Thanh; Khanh, Truong Huu; Tuan, Ha Manh; Viet, Ho Lu; Nam, Nguyen Tran; Viet, Do Chau; Qui, Phan Tu; Wills, Bridget; Sabanathan, Sarawathy; Chau, Nguyen Van Vinh; Thwaites, Louise; Rogier van Doorn, H.; Thwaites, Guy; Rabaa, Maia A.; Van Tan, Le;

Published:

Apr 2018

Source:

Emerg Infect Dis. 24(4):654-662.

Description:

Hand, foot and mouth disease (HFMD) is a major public health issue in Asia and has global pandemic potential. Coxsackievirus A6 (CV-A6) was detected in 514/2,230 (23%) of HFMD patients admitted to 3 major hospitals in southern Vietnam during 2011-201...

File Type:

[PDF - 2.67 MB]
Multirecombinant Enterovirus A71 Subgenogroup C1 Isolates Associated with Neurologic Disease, France, 2016–2017

Personal Author:

Ngangas, Stéphanie Tomba; Lukashev, Alexander; Jugie, Gwendoline; Ivanova, Olga; Mansuy, Jean-Michel; Mengelle, Catherine; Izopet, Jacques; L’honneur, Anne-Sophie; Rozenberg, Flore; Leyssene, David; Hecquet, Denise; Marque-Juillet, Stéphanie; Boutolleau, David; Burrel, Sonia; Peigue-Lafeuille, Hélène; Archimbaud, Christine; Benschop, Kimberley; Henquell, Cécile; Mirand, Audrey; Bailly, Jean-Luc;

Published:

Jun 2019

Source:

Emerg Infect Dis. 25(6):1204-1208

Description:

In 2016, an upsurge of neurologic disease associated with infection with multirecombinant enterovirus A71 subgenogroup C1 lineage viruses was reported in France. These viruses emerged in the 2000s; 1 recombinant is widespread. This virus lineage has ...

File Type:

[PDF - 1.88 MB]
Molecular epidemiology of coxsackievirus A6 associated with outbreaks of hand, foot, and mouth disease in Tianjin, China, in 2013

Personal Author:

Tan, Xiaojuan; Li, Li; Zhang, Baomin; Jorba, Jaume; Su, Xu; Ji, Tianjiao; Yang, Dongjing; Lv, Likun; Li, Jiameng; Xu, Wenbo;

Published:

Feb 15 2015

Source:

Arch Virol. 160(4):1097-1104.

Description:

Since 2008, Mainland China has undergone widespread outbreaks of hand, foot, and mouth disease (HFMD). In order to determine the characteristics of epidemics and enteroviruses (EV) associated with HFMD in Tianjin, in northern China, epidemiological a...

File Type:

[PDF - 482.51 KB]
Enterovirus and Parechovirus Surveillance — United States, 2014–2016

Personal Author:

Abedi, Glen R.; Watson, John T.; Nix, W. Allan; Oberste, M. Steven; Gerber, Susan I.;

Published:

May 11 2018

Source:

MMWR Morb Mortal Wkly Rep. 67(18):515-518.

Description:

Infections caused by enteroviruses (EV) and parechoviruses (PeV), members of the Picornaviridae family, are associated with various clinical manifestations, including hand, foot, and mouth disease; respiratory illness; myocarditis; meningitis; and se...

File Type:

[PDF - 145.63 KB]
Diphtheria Outbreak in Amerindian Communities, Wonken, Venezuela, 2016–2017

Personal Author:

Lodeiro-Colatosti, Adriana; Reischl, Udo; Holzmann, Thomas; Hernández-Pereira, Carlos E.; Rísquez, Alejandro; Paniz-Mondolfi, Alberto E.;

Published:

Jul 2018

Source:

Emerg Infect Dis. 24(7):1340-1344.

Description:

In February 2017, a diphtheria outbreak occurred among Amerindians of the Pemón ethnic group in Wonken, Venezuela. A field investigation revealed ≈10 cases; clinical presentation did not include cutaneous or neurologic signs or symptoms. To preven...

File Type:

[PDF - 1.27 MB]