The Penn Parkinson’s Daily Activities Questionnaire-15: Psychometric properties of a brief assessment of cognitive instrumental activities of daily living in Parkinson’s disease

Brennan, Laura; Siderowf, Andrew; Rubright, Jonathan D.; Rick, Jacqueline; Dahodwala, Nabila; Duda, John E.; Hurtig, Howard; Stern, Matthew; Xie, Sharon X.; Rennert, Lior; Karlawish, Jason; Shea, Judy A.; Trojanowski, John Q.; Weintraub, Daniel

doi:10.1016/j.parkreldis.2016.02.020

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The Penn Parkinson’s Daily Activities Questionnaire-15: Psychometric properties of a brief assessment of cognitive instrumental activities of daily living in Parkinson’s disease

Published Date:

Feb 21 2016

Publisher's site:

http://dx.doi.org/10.1016/j.parkreldis.2016.02.020 New Site Icon

Source:

Parkinsonism Relat Disord. 25:21-26.

[PDF-757.06 KB]

Details:

Personal Authors:

Brennan, Laura ; Siderowf, Andrew ; Rubright, Jonathan D. ; Rick, Jacqueline ; Dahodwala, Nabila ; ... More ▼

Keywords:

[+]

Pubmed ID:

26923524

Pubmed Central ID:

PMC4818172

Description:

Introduction

To describe the psychometric properties of the Penn Parkinson’s Daily Activities Questionnaire-15 (PDAQ-15), a 15-item measure of cognitive instrumental activities of daily living for Parkinson’s disease (PD) patients derived from the original 50-item PDAQ.

Methods

PDAQ-15 items were chosen by expert consensus. Knowledgeable informants of PD participants (n=161) completed the PDAQ-15. Knowledgeable informants were defined as an individual having regular contact with the PD participant. PD participants were assigned a diagnosis of normal cognition, mild cognitive impairment, or dementia based on expert consensus.

Results

PDAQ-15 scores correlated strongly with global cognition (Dementia Rating Scale-2, r=0.71, p<0.001) and a performance-based functional measure (Direct Assessment of Functional Status, r=0.83; p<0.001). PDAQ-15 scores accurately discriminated between non-demented PD participants (normal cognition/mild cognitive impairment) and PD with dementia (ROC curve area=0.91), with and without any cognitive impairment (normal cognition versus mild cognitive impairment/dementia, ROC curve area=0.85) and between participants with mild cognitive impairment and dementia (ROC curve area=0.84).

Conclusions

The PDAQ-15 shows good discriminant validity across cognitive stages, correlates highly with global cognitive performance, and appears suitable to assess daily cognitive functioning in PD.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

Main Document Checksum:

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