Details:

Alternative Title:
Parkinsonism Relat Disord
Publisher's site:
http://dx.doi.org/10.1016/j.parkreldis.2016.02.020
Personal Author:
Brennan, Laura ; Siderowf, Andrew ; Rubright, Jonathan D. ; Rick, Jacqueline ; Dahodwala, Nabila ; ... More +
Brennan, Laura ; Siderowf, Andrew ; Rubright, Jonathan D. ; Rick, Jacqueline ; Dahodwala, Nabila ; Duda, John E. ; Hurtig, Howard ; Stern, Matthew ; Xie, Sharon X. ; Rennert, Lior ; Karlawish, Jason ; Shea, Judy A. ; Trojanowski, John Q. ; Weintraub, Daniel ; Less -
Description:
Introduction To describe the psychometric properties of the Penn Parkinson’s Daily Activities Questionnaire-15 (PDAQ-15), a 15-item measure of cognitive instrumental activities of daily living for Parkinson’s disease (PD) patients derived from the original 50-item PDAQ. Methods PDAQ-15 items were chosen by expert consensus. Knowledgeable informants of PD participants (n=161) completed the PDAQ-15. Knowledgeable informants were defined as an individual having regular contact with the PD participant. PD participants were assigned a diagnosis of normal cognition, mild cognitive impairment, or dementia based on expert consensus. Results PDAQ-15 scores correlated strongly with global cognition (Dementia Rating Scale-2, r=0.71, p<0.001) and a performance-based functional measure (Direct Assessment of Functional Status, r=0.83; p<0.001). PDAQ-15 scores accurately discriminated between non-demented PD participants (normal cognition/mild cognitive impairment) and PD with dementia (ROC curve area=0.91), with and without any cognitive impairment (normal cognition versus mild cognitive impairment/dementia, ROC curve area=0.85) and between participants with mild cognitive impairment and dementia (ROC curve area=0.84). Conclusions The PDAQ-15 shows good discriminant validity across cognitive stages, correlates highly with global cognitive performance, and appears suitable to assess daily cognitive functioning in PD.
Subject:
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Activities Of Daily Living
Aged
Article
Cognition Disorders
Female
Humans
Male
Parkinson Disease
Psychometrics
Surveys And Questionnaires

Source:
Parkinsonism Relat Disord. 25:21-26. ;
Pubmed ID:
26923524
Pubmed Central ID:
PMC4818172
Document Type:
Journal Article ;
Funding:
P30 AG010124/AG/NIA NIH HHS/United States ; T32 MH065218/MH/NIMH NIH HHS/United States ; P01 AG017586/AG/NIA NIH HHS/United States ; U01 AG024904/AG/NIA NIH HHS/United States ; R01 AG025152/AG/NIA NIH HHS/United States ; ... More +
P30 AG010124/AG/NIA NIH HHS/United States ; T32 MH065218/MH/NIMH NIH HHS/United States ; P01 AG017586/AG/NIA NIH HHS/United States ; U01 AG024904/AG/NIA NIH HHS/United States ; R01 AG025152/AG/NIA NIH HHS/United States ; R01 NS065087/NS/NINDS NIH HHS/United States ; U48 DP005053/DP/NCCDPHP CDC HHS/United States ; R01 AG038440/AG/NIA NIH HHS/United States ; P50 NS053488/NS/NINDS NIH HHS/United States ; K23 AG034236/AG/NIA NIH HHS/United States ; U01 AG010483/AG/NIA NIH HHS/United States ; NS-053488/NS/NINDS NIH HHS/United States ; U01 AG029213/AG/NIA NIH HHS/United States ; Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:d5c02458167f57af81137c5d4a04771cfb83a063f510b4cf242f258fd95aabc4
File Type:

Supporting Files

• 	NIHMS763979-supplement.docx	docx
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