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The Penn Parkinson’s Daily Activities Questionnaire-15: Psychometric properties of a brief assessment of cognitive instrumental activities of daily living in Parkinson’s disease
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Details:
  • Pubmed ID:
    26923524
  • Pubmed Central ID:
    PMC4818172
  • Description:
    Introduction

    To describe the psychometric properties of the Penn Parkinson’s Daily Activities Questionnaire-15 (PDAQ-15), a 15-item measure of cognitive instrumental activities of daily living for Parkinson’s disease (PD) patients derived from the original 50-item PDAQ.

    Methods

    PDAQ-15 items were chosen by expert consensus. Knowledgeable informants of PD participants (n=161) completed the PDAQ-15. Knowledgeable informants were defined as an individual having regular contact with the PD participant. PD participants were assigned a diagnosis of normal cognition, mild cognitive impairment, or dementia based on expert consensus.

    Results

    PDAQ-15 scores correlated strongly with global cognition (Dementia Rating Scale-2, r=0.71, p<0.001) and a performance-based functional measure (Direct Assessment of Functional Status, r=0.83; p<0.001). PDAQ-15 scores accurately discriminated between non-demented PD participants (normal cognition/mild cognitive impairment) and PD with dementia (ROC curve area=0.91), with and without any cognitive impairment (normal cognition versus mild cognitive impairment/dementia, ROC curve area=0.85) and between participants with mild cognitive impairment and dementia (ROC curve area=0.84).

    Conclusions

    The PDAQ-15 shows good discriminant validity across cognitive stages, correlates highly with global cognitive performance, and appears suitable to assess daily cognitive functioning in PD.

  • Document Type:
  • Collection(s):
  • Funding:
    P30 AG010124/AG/NIA NIH HHS/United States
    T32 MH065218/MH/NIMH NIH HHS/United States
    P01 AG017586/AG/NIA NIH HHS/United States
    U01 AG024904/AG/NIA NIH HHS/United States
    R01 AG025152/AG/NIA NIH HHS/United States
    R01 NS065087/NS/NINDS NIH HHS/United States
    U48 DP005053/DP/NCCDPHP CDC HHS/United States
    R01 AG038440/AG/NIA NIH HHS/United States
    P50 NS053488/NS/NINDS NIH HHS/United States
    K23 AG034236/AG/NIA NIH HHS/United States
    U01 AG010483/AG/NIA NIH HHS/United States
    NS-053488/NS/NINDS NIH HHS/United States
    U01 AG029213/AG/NIA NIH HHS/United States
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