Severe Panuveitis, Retinal Vasculitis, and Optic Disc Granuloma Secondary to Sarcoidosis
Source:Retin Cases Brief Rep. 10(4):341-344.
Pubmed Central ID:PMC4899314
Funding:P30 EY006360/EY/NEI NIH HHS/United States
U50 DP523414/DP/NCCDPHP CDC HHS/United States
To report a case of panuveitis, retinal vasculitis, and optic disc granuloma due to sarcoidosis.
Case report and literature review.
A 26 year-old previously healthy African American male presented with four months of gradual progressive visual decline in the right eye. Clinical examination revealed severe panuveitis, retinal vasculitis, and large optic nerve mass lesion. Diffuse supraclavicular lymphadenopathy was also present. Histopathologic examination of the lymph node biopsy revealed granulomatous inflammation with some areas of casseous necrosis, consistent with sarcoidosis.
Sarcoidosis is a common cause of uveitis and retinal vasculitis. In rare cases, an optic disc granuloma may occur and can be treated with immunosuppressive therapy.
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