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Deletion Variants of Middle East Respiratory Syndrome Coronavirus from Humans, Jordan, 2015
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  1. Multihospital Outbreak of a Middle East Respiratory Syndrome Coronavirus Deletion Variant, Jordan: A Molecular, Serologic, and Epidemiologic Investigation
    Personal Author:
    Payne, Daniel C.; Biggs, Holly M.; Al-Abdallat, Mohammad Mousa; Alqasrawi, Sultan; Lu, Xiaoyan; Abedi, Glen R.; Haddadin, Aktham; Iblan, Ibrahim; Alsanouri, Tarek; Al Nsour, Mohannad; Sheikh Ali, Sami; Rha, Brian; Trivedi, Suvang U.; Rasheed, Mohammed Ata Ur; Tamin, Azaibi; Lamers, Mart M.; Haagmans, Bart L.; Erdman, Dean D.; Thornburg, Natalie J.; Gerber, Susan I.;
    Published Date:
    Apr 28 2018
    Source:
    Open Forum Infect Dis. 2018; 5(5).
    Description:
    BackgroundAn outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) in Jordan in 2015 involved a variant virus that acquired distinctive deletions in the accessory open reading frames. We conducted a molecular and seroepidemiologic inves...
    File Type:
    Filetype[PDF - 265.64 KB]
  2. Spike gene deletion quasispecies in serum of patient with acute MERS‐CoV infection
    Personal Author:
    Lu, Xiaoyan; Rowe, Lori A.; Frace, Michael; Stevens, James; Abedi, Glen R.; Elnile, Osman; Banassir, Taleb; Al‐Masri, Malak; Watson, John T.; Assiri, Abdullah; Erdman, Dean D.;
    Published Date:
    August 22 2016
    Source:
    J Med Virol. 89(3):542-545
    Description:
    The spike glycoprotein of the Middle East respiratory coronavirus (MERS-CoV) facilitates receptor binding and cell entry. During investigation of a multi-facility outbreak of MERS-CoV in Taif, Saudi Arabia, we identified a mixed population of wild-ty...
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  3. Middle East Respiratory Syndrome Coronavirus Transmission
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    Killerby, Marie E.; Biggs, Holly M.; Midgley, Claire M.; Gerber, Susan I.; Watson, John T.;
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    Feb 2020
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    Emerg Infect Dis. 26(2):191-198
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    Middle East respiratory syndrome coronavirus (MERS-CoV) infection causes a spectrum of respiratory illness, from asymptomatic to mild to fatal. MERS-CoV is transmitted sporadically from dromedary camels to humans and occasionally through human-to-hum...
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  4. MERS Coronaviruses in Dromedary Camels, Egypt
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    Chu, Daniel K.W.; Poon, Leo L.M.; Gomaa, Mokhtar M.; Shehata, Mahmoud M.; Perera, Ranawaka A.P.M.; Abu Zeid, Dina; El Rifay, Amira S.; Siu, Lewis Y.; Guan, Yi; Webby, Richard J.; Ali, Mohamed A.; Peiris, Malik; Kayali, Ghazi;
    Published Date:
    Jun 2014
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    Emerg Infect Dis. 20(6):1049-1053.
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    We identified the near-full-genome sequence (29,908 nt, >99%) of Middle East respiratory syndrome coronavirus (MERS-CoV) from a nasal swab specimen from a dromedary camel in Egypt. We found that viruses genetically very similar to human MERS-CoV are ...
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    Gould, L. Hannah; Kline, Jennifer; Monahan, Caitlin; Vierk, Katherine;
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    Mar 2017
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    Emerg Infect Dis. 23(3):525-528.
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    The proportion of US food that is imported is increasing; most seafood and half of fruits are imported. We identified a small but increasing number of foodborne disease outbreaks associated with imported foods, most commonly fish and produce. New out...
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