Limited Dissemination of Extended-Spectrum β-Lactamase– and Plasmid-Encoded AmpC–Producing Escherichia coli from Food and Farm Animals, Sweden

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Börjesson, Stefan ; Ny, Sofia ; Egervärn, Maria ; Bergström, Jakob ; Rosengren, Åsa ; Englund, Stina ; Löfmark, Sonja ; Byfors, Sara
• Description:
  Extended-spectrum β-lactamase (ESBL)- and plasmid-encoded ampC (pAmpC)-producing Enterobacteriaceae might spread from farm animals to humans through food. However, most studies have been limited in number of isolates tested and areas studied. We examined genetic relatedness of 716 isolates from 4,854 samples collected from humans, farm animals, and foods in Sweden to determine whether foods and farm animals might act as reservoirs and dissemination routes for ESBL/pAmpC-producing Escherichia coli. Results showed that clonal spread to humans appears unlikely. However, we found limited dissemination of genes encoding ESBL/pAmpC and plasmids carrying these genes from foods and farm animals to healthy humans and patients. Poultry and chicken meat might be a reservoir and dissemination route to humans. Although we found no evidence of clonal spread of ESBL/pAmpC-producing E. coli from farm animals or foods to humans, ESBL/pAmpC-producing E. coli with identical genes and plasmids were present in farm animals, foods, and humans.
• Subjects:
  Antimicrobial Resistance Bacteria Bloodstream Infections Broilers Carriage ESBL Escherichia Coli Extended-spectrum Cephalosporin Extended-spectrum β-lactamase Farm Animals Foodborne Infections Limited Dissemination Of Extended-Spectrum β-Lactamase– And Plasmid-Encoded AmpC–Producing Escherichia Coli From Food And Farm Animals, Sweden Meat National Assessment PAmpC Plasmid-encoded AmpC Poultry Research Sweden

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• Source:
  Emerg Infect Dis. 22(4):634-640.
• Pubmed ID:
  26982890
• Pubmed Central ID:
  PMC4806949
• Document Type:
  Journal Article
• Volume:
  22
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:3b043535836107bb68ea0324832ee7466a95689e9ee7771b79addd4a6a68ac0a
• Download URL:
  https://stacks.cdc.gov/view/cdc/38710/cdc_38710_DS1.pdf
• File Type:
  [PDF - 769.56 KB ]