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Why build whole-cell models?
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    Personal Author:
    Karr, Jonathan R.; Williams, Alex H.; Zucker, Jeremy D.; Raue, Andreas; Steiert, Bernhard; Timmer, Jens; Kreutz, Clemens; Wilkinson, Simon; Allgood, Brandon A.; Bot, Brian M.; Hoff, Bruce R.; Kellen, Michael R.; Covert, Markus W.; Stolovitzky, Gustavo A.; Meyer, Pablo;
    Corporate Author:
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    Published:
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    Source:
    PLoS Comput Biol. 2015; 11(5).
    Description:
    Whole-cell models that explicitly represent all cellular components at the molecular level have the potential to predict phenotype from genotype. However, even for simple bacteria, whole-cell models will contain thousands of parameters, many of which...
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    The Whole School, Whole Community, Whole Child (WSCC) model expands on the eight elements of CDC’s coordinated school health ( CSH ) approach and is combined with the whole child framework. CDC and ASCD developed this expanded model—in collaborat...
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