Why build whole-cell models?

Carrera, Javier; Covert, Markus W.

doi:10.1016/j.tcb.2015.09.004

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

i

Why build whole-cell models?

Oct 21 2015
By Carrera, Javier ; Covert, Markus W.
http://dx.doi.org/10.1016/j.tcb.2015.09.004
Source: Trends Cell Biol. 25(12):719-722.

[PDF-103.52 KB]

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Details:

Alternative Title:

Trends Cell Biol
Personal Author:

Carrera, Javier ; Covert, Markus W.

Carrera, Javier ; Covert, Markus W. Less -
Description:

Our ability to build computational models that account for all known gene functions in a cell has increased dramatically. But why build whole-cell models, and how can they best be used? In this forum, we enumerate several areas in which whole-cell modeling can significantly impact research and technology.
Subjects:

[+]

Animals Article Cell Physiological Phenomena Computational Biology Humans Model-driven Discovery Models, Biological Predictive Biology Whole-cell Modeling
Source:

Trends Cell Biol. 25(12):719-722.
Pubmed ID:

26471224
Pubmed Central ID:

PMC4663153
Document Type:

Journal Article
Funding:

DP1 LM011510/LM/NLM NIH HHS/United States ; P50 GM107615/GM/NIGMS NIH HHS/United States ; 5DP1LM01150-05/DP/NCCDPHP CDC HHS/United States ; P50GM107615/GM/NIGMS NIH HHS/United States ; DP1 OD006413/OD/NIH HHS/United States

DP1 LM011510/LM/NLM NIH HHS/United States ; P50 GM107615/GM/NIGMS NIH HHS/United States ; 5DP1LM01150-05/DP/NCCDPHP CDC HHS/United States ; P50GM107615/GM/NIGMS NIH HHS/United States ; DP1 OD006413/OD/NIH HHS/United States Less -
Volume:

25
Issue:

12
Collection(s):

CDC Public Access
Main Document Checksum:

[+]

urn:sha256:9998d88e3d71c36d525f9e49db1b27451ed9b0f3236462f5c9927c30afac6700
Download URL:

https://stacks.cdc.gov/view/cdc/38310/cdc_38310_DS1.pdf
File Type:

	nihms725166.nxml	bin
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	nihms725166f1.jpg	jpeg

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