WholeCellViz: data visualization for whole-cell models

Lee, Ruby; Karr, Jonathan R; Covert, Markus W

doi:10.1186/1471-2105-14-253

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WholeCellViz: data visualization for whole-cell models

Published Date:

Aug 21 2013

Publisher's site:

http://dx.doi.org/10.1186/1471-2105-14-253 New Site Icon

Source:

BMC Bioinformatics. 2013; 14:253.

[PDF-1.84 MB]

Details:

Personal Authors:

Lee, Ruby ; Karr, Jonathan R ; Covert, Markus W ;

Keywords:

[+]

Pubmed ID:

23964998

Pubmed Central ID:

PMC3765349

Description:

Background

Whole-cell models promise to accelerate biomedical science and engineering. However, discovering new biology from whole-cell models and other high-throughput technologies requires novel tools for exploring and analyzing complex, high-dimensional data.

Results

We developed WholeCellViz, a web-based software program for visually exploring and analyzing whole-cell simulations. WholeCellViz provides 14 animated visualizations, including metabolic and chromosome maps. These visualizations help researchers analyze model predictions by displaying predictions in their biological context. Furthermore, WholeCellViz enables researchers to compare predictions within and across simulations by allowing users to simultaneously display multiple visualizations.

Conclusion

WholeCellViz was designed to facilitate exploration, analysis, and communication of whole-cell model data. Taken together, WholeCellViz helps researchers use whole-cell model simulations to drive advances in biology and bioengineering.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

5DP1LM01150-05/DP/NCCDPHP CDC HHS/United States
DP1 LM011510/LM/NLM NIH HHS/United States
DP1 OD006413/OD/NIH HHS/United States

Supporting Files:

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