Details:

Alternative Title:
BMC Bioinformatics
Publisher's site:
http://dx.doi.org/10.1186/1471-2105-14-253
Personal Author:
Lee, Ruby ; Karr, Jonathan R ; Covert, Markus W
Lee, Ruby ; Karr, Jonathan R ; Covert, Markus W Less -
Description:
Background

Whole-cell models promise to accelerate biomedical science and engineering. However, discovering new biology from whole-cell models and other high-throughput technologies requires novel tools for exploring and analyzing complex, high-dimensional data.

Results

We developed WholeCellViz, a web-based software program for visually exploring and analyzing whole-cell simulations. WholeCellViz provides 14 animated visualizations, including metabolic and chromosome maps. These visualizations help researchers analyze model predictions by displaying predictions in their biological context. Furthermore, WholeCellViz enables researchers to compare predictions within and across simulations by allowing users to simultaneously display multiple visualizations.

Conclusion

WholeCellViz was designed to facilitate exploration, analysis, and communication of whole-cell model data. Taken together, WholeCellViz helps researchers use whole-cell model simulations to drive advances in biology and bioengineering.


Subject:
[+]
Bacteria
Cell Cycle
Cell Physiology
Chromosome Mapping
Computational Biology
Computer Simulation
Databases, Factual
Databases, Genetic
Data Visualization
Internet
Models, Biological
Mycoplasma
Software
Systems Biology
Whole-cell Modeling
Computational Biology

Source:
BMC Bioinformatics. 2013; 14:253.
Pubmed ID:
23964998
Pubmed Central ID:
PMC3765349
Document Type:
Journal Article
Funding:
5DP1LM01150-05/DP/NCCDPHP CDC HHS/United States ; DP1 LM011510/LM/NLM NIH HHS/United States ; DP1 OD006413/OD/NIH HHS/United States
5DP1LM01150-05/DP/NCCDPHP CDC HHS/United States ; DP1 LM011510/LM/NLM NIH HHS/United States ; DP1 OD006413/OD/NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:d29e44746067fa6dc8861f6c700a618e7c14f41e1be280ac3034d4592b6b87d0
File Type:

Supporting Files

• 	1471-2105-14-253.nxml	txt
  	license.txt	txt
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