Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015

Seong, Moon-Woo; Kim, So Yeon; Corman, Victor Max; Kim, Taek Soo; Cho, Sung Im; Kim, Man Jin; Lee, Seung Jun; Lee, Jee-Soo; Seo, Soo Hyun; Ahn, Ji Soo; Yu, Byeong Su; Park, Nare; Oh, Myoung-don; Park, Wan Beom; Lee, Ji Yeon; Kim, Gayeon; Joh, Joon Sung; Jeong, Ina; Kim, Eui Chong; Drosten, Christian; Park, Sung Sup

doi:10.3201/eid2202.151700

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015

Published Date:

Feb 2016

Publisher's site:

http://dx.doi.org/10.3201/eid2202.151700 New Site Icon

Source:

Emerg Infect Dis. 22(2):327-330.

[PDF-416.16 KB]

Details:

Personal Authors:

Seong, Moon-Woo ; Kim, So Yeon ; Corman, Victor Max ; Kim, Taek Soo ; Cho, Sung Im ; ... More ▼

Keywords:

[+]

Pubmed ID:

26814649

Pubmed Central ID:

PMC4734539

Description:

During the 2015 Middle East respiratory syndrome coronavirus outbreak in South Korea, we sequenced full viral genomes of strains isolated from 4 patients early and late during infection. Patients represented at least 4 generations of transmission. We found no evidence of changes in the evolutionary rate and no reason to suspect adaptive changes in viral proteins.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

	15-1700-F1.gif	image/gif
	15-1700-F1.jpg	image/jpeg
	15-1700-F2.gif	image/gif
	15-1700-F2.jpg	image/jpeg
	15-1700-Techapp-s1.pdf	application/pdf
	15-1700.nxml	application/octet-stream

No Related Documents.

You May Also Like:

Deletion Variants of Middle East Respiratory Syndrome Coronavirus from Humans, Jordan, 2015

Personal Author:

Lamers, Mart M.; Raj, V. Stalin; Shafei, Mah’d; Ali, Sami Sheikh; Abdallh, Sultan M.; Gazo, Mahmoud; Nofal, Samer; Lu, Xiaoyan; Erdman, Dean D.; Koopmans, Marion P.; Abdallat, Mohammad; Haddadin, Aktham; Haagmans, Bart L.;

Published:

Apr 2016

Source:

Emerg Infect Dis. 22(4):716-719.

Description:

We characterized Middle East respiratory syndrome coronaviruses from a hospital outbreak in Jordan in 2015. The viruses from Jordan were highly similar to isolates from Riyadh, Saudi Arabia, except for deletions in open reading frames 4a and 3. Trans...

File Type:

[PDF - 584.33 KB]
$Variations in Spike Glycoprotein Gene of MERSCoV South Korea 2015$

Variations in Spike Glycoprotein Gene of MERS-CoV, South Korea, 2015

Personal Author:

Kim, Dae-Won; Kim, You-Jin; Park, Sung Han; Yun, Mi-Ran; Yang, Jeong-Sun; Kang, Hae Ji; Han, Young Woo; Lee, Han Saem; Man Kim, Heui; Kim, Hak; Kim, A-Reum; Heo, Deok Rim; Kim, Su Jin; Jeon, Jun Ho; Park, Deokbum; Kim, Joo Ae; Cheong, Hyang-Min; Nam, Jeong-Gu; Kim, Kisoon; Kim, Sung Soon;

Published:

Jan 2016

Source:

Emerg Infect Dis. 22(1):100-104.

Description:

An outbreak of nosocomial infections with Middle East respiratory syndrome coronavirus occurred in South Korea in May 2015. Spike glycoprotein genes of virus strains from South Korea were closely related to those of strains from Riyadh, Saudi Arabia....

File Type:

[PDF - 643.38 KB]
Mortality Risk Factors for Middle East Respiratory Syndrome Outbreak, South Korea, 2015

Personal Author:

Majumder, Maimuna S.; Kluberg, Sheryl A.; Mekaru, Sumiko R.; Brownstein, John S.;

Published:

Nov 2015

Source:

Emerg Infect Dis. 21(11):2088-2090.

Description:

As of July 15, 2015, the South Korean Ministry of Health and Welfare had reported 186 case-patients with Middle East respiratory syndrome in South Korea. For 159 case-patients with known outcomes and complete case histories, we found that older age a...

File Type:

[PDF - 351.82 KB]
Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea

Personal Author:

Park, Wan Beom; Perera, Ranawaka A.P.M.; Choe, Pyoeng Gyun; Lau, Eric H.Y.; Choi, Seong Jin; Chun, June Young; Oh, Hong Sang; Song, Kyoung-Ho; Bang, Ji Hwan; Kim, Eu Suk; Kim, Hong Bin; Park, Sang Won; Kim, Nam Joong; Man Poon, Leo Lit; Peiris, Malik; Oh, Myoung-don;

Published:

Dec 2015

Source:

Emerg Infect Dis. 21(12):2186-2189.

Description:

We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody responses developed by the third...

File Type:

[PDF - 450.83 KB]
Viral RNA in Blood as Indicator of Severe Outcome in Middle East Respiratory Syndrome Coronavirus Infection

Personal Author:

Kim, So Yeon; Park, Sun Jae; Cho, Sook Young; Cha, Ran-hui; Jee, Hyeon-Gun; Kim, Gayeon; Shin, Hyoung-Shik; Kim, Yeonjae; Jung, Yu Mi; Yang, Jeong-Sun; Kim, Sung Soon; Cho, Sung Im; Kim, Man Jin; Lee, Jee-Soo; Lee, Seung Jun; Seo, Soo Hyun; Park, Sung Sup; Seong, Moon-Woo;

Published:

Oct 15 2016

Source:

Emerg Infect Dis. 22(10):1813-1816.

Description:

We evaluated the diagnostic and clinical usefulness of blood specimens to detect Middle East respiratory syndrome coronavirus infection in 21 patients from the 2015 outbreak in South Korea. Viral RNA was detected in blood from 33% of patients at init...

File Type:

[PDF - 1.28 MB]