Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Seong, Moon-Woo ; Kim, So Yeon ; Corman, Victor Max ; Kim, Taek Soo ; Cho, Sung Im ; Kim, Man Jin ; Lee, Seung Jun ; Lee, Jee-Soo ; Seo, Soo Hyun ; Ahn, Ji Soo ; Yu, Byeong Su ; Park, Nare ; Oh, Myoung-don ; Park, Wan Beom ; Lee, Ji Yeon ; Kim, Gayeon ; Joh, Joon Sung ; Jeong, Ina ; Kim, Eui Chong ; Drosten, Christian ; Park, Sung Sup
• Description:
  During the 2015 Middle East respiratory syndrome coronavirus outbreak in South Korea, we sequenced full viral genomes of strains isolated from 4 patients early and late during infection. Patients represented at least 4 generations of transmission. We found no evidence of changes in the evolutionary rate and no reason to suspect adaptive changes in viral proteins.
• Subjects:
  Adult Coronavirus Infections Disease Outbreaks Dispatch Evolution, Molecular Genetic Variation Genome, Viral History, 21st Century Humans Male Middle East Respiratory Syndrome Coronavirus

  More +
• Source:
  Emerg Infect Dis. 22(2):327-330.
• Pubmed ID:
  26814649
• Pubmed Central ID:
  PMC4734539
• Document Type:
  Journal Article
• Place as Subject:
  Republic of Korea
• Location:
  Asia
• Volume:
  22
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:42598539f401d56e4a313d80183a7de1afba7400c707c3650959afff2aa42328
• Download URL:
  https://stacks.cdc.gov/view/cdc/38013/cdc_38013_DS1.pdf
• File Type:
  [PDF - 416.16 KB ]