Trematode Fluke Procerovum varium as Cause of Ocular Inflammation in Children, South India

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Arya, Lalan Kumar ; Rathinam, Sivakumar R. ; Lalitha, Prajna ; Kim, Usha R. ; Ghatani, Sudeep ; Tandon, Veena
• Description:
  Trematodes are recognized as a group of emerging parasites in tropical countries. We identified a trematode as a cause of ocular granulomas that developed in children who bathed in ponds or rivers in South India. DNA was isolated from patients' surgically excised granulomas and from the trematode cercariae (larvae) released by the snail Melanoides tuberculata in water in which the children bathed. Real-time and conventional PCRs were performed that targeted ribosomal DNA regions spanning the internal transcribed spacer 2 and 28S sequences of this trematode. The PCR-amplified products were subjected to bidirectional sequencing. Analysis of sequences for the granuloma samples and the trematode cercariae showed maximum sequence similarity with Procerovum varium (family Heterophyidae). Our results confirmed the etiology of the ocular infection, implicating snail vectors as environmental risk factors for ocular parasitosis.
• Subjects:
  Adolescent Animals Base Sequence Child DNA, Helminth Eye Infections, Parasitic Female Geography Granuloma Humans Male Molecular Sequence Data Research Sequence Alignment Sequence Analysis, DNA Snails Trematoda Trematode Infections

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• Source:
  Emerg Infect Dis. 22(2):192-200.
• Pubmed ID:
  26812231
• Pubmed Central ID:
  PMC4734527
• Document Type:
  Journal Article
• Place as Subject:
  India
• Location:
  Asia
• Volume:
  22
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:a9c4440c34c40c45fe1e9803bff7cd98372e53df9dfb9aa77a065cb6d8610098
• Download URL:
  https://stacks.cdc.gov/view/cdc/37978/cdc_37978_DS1.pdf
• File Type:
  [PDF - 772.45 KB ]