Risk Factors for Primary Middle East Respiratory Syndrome Coronavirus Illness in Humans, Saudi Arabia, 2014

Alraddadi, Basem M.; Watson, John T.; Almarashi, Abdulatif; Abedi, Glen R.; Turkistani, Amal; Sadran, Musallam; Housa, Abeer; Almazroa, Mohammad A.; Alraihan, Naif; Banjar, Ayman; Albalawi, Eman; Alhindi, Hanan; Choudhry, Abdul Jamil; Meiman, Jonathan G.; Paczkowski, Magdalena; Curns, Aaron; Mounts, Anthony; Feikin, Daniel R.; Marano, Nina; Swerdlow, David L.; Gerber, Susan I.; Hajjeh, Rana; Madani, Tariq A.

doi:10.3201/eid2201.151340

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Risk Factors for Primary Middle East Respiratory Syndrome Coronavirus Illness in Humans, Saudi Arabia, 2014

Supporting Files Public Domain

Jan 2016
By Alraddadi, Basem M. ; Watson, John T. ; Almarashi, Abdulatif ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Alraddadi, Basem M. ; Watson, John T. ; Almarashi, Abdulatif ; Abedi, Glen R. ; Turkistani, Amal ; Sadran, Musallam ; Housa, Abeer ; Almazroa, Mohammad A. ; Alraihan, Naif ; Banjar, Ayman ; Albalawi, Eman ; Alhindi, Hanan ; Choudhry, Abdul Jamil ; Meiman, Jonathan G. ; Paczkowski, Magdalena ; Curns, Aaron ; Mounts, Anthony ; Feikin, Daniel R. ; Marano, Nina ; Swerdlow, David L. ; Gerber, Susan I. ; Hajjeh, Rana ; Madani, Tariq A.
Description:

Risk factors for primary Middle East respiratory syndrome coronavirus (MERS-CoV) illness in humans are incompletely understood. We identified all primary MERS-CoV cases reported in Saudi Arabia during March-November 2014 by excluding those with history of exposure to other cases of MERS-CoV or acute respiratory illness of unknown cause or exposure to healthcare settings within 14 days before illness onset. Using a case-control design, we assessed differences in underlying medical conditions and environmental exposures among primary case-patients and 2-4 controls matched by age, sex, and neighborhood. Using multivariable analysis, we found that direct exposure to dromedary camels during the 2 weeks before illness onset, as well as diabetes mellitus, heart disease, and smoking, were each independently associated with MERS-CoV illness. Further investigation is needed to better understand animal-to-human transmission of MERS-CoV.
Subjects:

Adult Aged Animals Camelus Case-Control Studies Coronavirus Infections Female Humans Male Middle Aged Risk Factors Young Adult
Source:

Emerg Infect Dis. 22(1):49-55.
Pubmed ID:

26692185
Pubmed Central ID:

PMC4696714
Document Type:

Journal Article
Place as Subject:

Saudi Arabia
Volume:

22
Issue:

1
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:568d92824f856ff67dc7822b855d715d4429eb9d6134e1a21e5e22e61b38f63f
Download URL:

https://stacks.cdc.gov/view/cdc/37295/cdc_37295_DS1.pdf
File Type:

[PDF - 449.07 KB ]

File Language:

English

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