Pathogenesis and Disease Mechanisms of Occupational Asthma

Details

• Alternative Title:
  Immunol Allergy Clin North Am
• Personal Author:
  Lummus, Zana L. ; Wisnewski, Adam V. ; Bernstein, David I.
• Description:
  Occupational asthma (OA) is one of the most common forms of work-related lung disease in all industrialized nations. The clinical management of patients with OA depends on an understanding of the multifactorial pathogenetic mechanisms that can contribute to this disease. This article discusses the various immunologic and nonimmunologic mechanisms and genetic susceptibility factors that drive the inflammatory processes of OA.
• Subjects:
  Airway Remodeling Allergens Asthma, Occupational Bronchial Hyperreactivity Genetic Predisposition To Disease Humans Immunity, Innate Immunoglobulin E Irritants Occupational Exposure Oxidative Stress Risk Factors

  More +
• Source:
  Immunol Allergy Clin North Am. 31(4):699-vi.
• Pubmed ID:
  21978852
• Pubmed Central ID:
  PMC4683932
• Document Type:
  Journal Article
• Funding:
  R01 OH008795/OH/NIOSH CDC HHS/United States ; R21 OH010438/OH/NIOSH CDC HHS/United States ; R41 ES018021/ES/NIEHS NIH HHS/United States ; R42 ES016728/ES/NIEHS NIH HHS/United States ; R42 ES018021/ES/NIEHS NIH HHS/United States ; T32 AI060515/AI/NIAID NIH HHS/United States
• Volume:
  31
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:e524c5e0258b98d6b57094ff21853743468decb0edef46782d3d500beb031425
• Download URL:
  https://stacks.cdc.gov/view/cdc/36914/cdc_36914_DS1.pdf
• File Type:
  [PDF - 191.11 KB ]