Pathogenesis and Disease Mechanisms of Occupational Asthma
Published Date:Nov 2011
Source:Immunol Allergy Clin North Am. 31(4):699-vi.
Genetic Predisposition To Disease
Pubmed Central ID:PMC4683932
Funding:R01 OH008795/OH/NIOSH CDC HHS/United States
R21 OH010438/OH/NIOSH CDC HHS/United States
R41 ES018021/ES/NIEHS NIH HHS/United States
R42 ES016728/ES/NIEHS NIH HHS/United States
R42 ES018021/ES/NIEHS NIH HHS/United States
T32 AI060515/AI/NIAID NIH HHS/United States
Description:Occupational asthma (OA) is one of the most common forms of work-related lung disease in all industrialized nations. The clinical management of patients with OA depends on an understanding of the multifactorial pathogenetic mechanisms that can contribute to this disease. This article discusses the various immunologic and nonimmunologic mechanisms and genetic susceptibility factors that drive the inflammatory processes of OA.
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