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Using Data to Guide Policy: Next Steps for Preventing Perinatal Hepatitis B Virus Transmission in Cambodia
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12 17 2012
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Source: Vaccine. 31(1):149-153
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Alternative Title:Vaccine
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Description:Cambodia is highly endemic for hepatitis B virus (HBV) infection. Preventing perinatal HBV transmission should be prioritized in health facilities by providing hepatitis B vaccination to all infants within 24 h of birth (timely birth dose coverage).|Teams assessed birth dose policy, practices and coverage in hospitals and health facilities in 10 provinces in Cambodia.|Fifty-one sites were assessed. Median (interquartile range) timely birth dose coverage was 66% (48-92%); coverage was 88% (range=60-96%) in facilities vaccinating on-site and 48% (range=20-52%) in those referring off-site (p<0.0001). Overall, 5 (29%) of 16 hospitals that referred vaccination off-site did not tell mothers vaccination should take place within 24 h of birth, and 6 (35%) discharged mothers when no vaccination services were available for infants to receive the birth dose.|Newborns can miss a time-sensitive opportunity to be protected against perinatal HBV infection when they are referred for vaccination off-site rather than being vaccinated in the delivery facility. These data support the case to strengthen policies and practices to provide hepatitis B birth dose vaccination in the delivery facility.
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Pubmed ID:23127515
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Pubmed Central ID:PMC4663666
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Volume:31
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Issue:1
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