Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Park, Wan Beom ; Perera, Ranawaka A.P.M. ; Choe, Pyoeng Gyun ; Lau, Eric H.Y. ; Choi, Seong Jin ; Chun, June Young ; Oh, Hong Sang ; Song, Kyoung-Ho ; Bang, Ji Hwan ; Kim, Eu Suk ; Kim, Hong Bin ; Park, Sang Won ; Kim, Nam Joong ; Man Poon, Leo Lit ; Peiris, Malik ; Oh, Myoung-don
• Description:
  We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody responses developed by the third week of illness. Delayed antibody responses with the neutralization test were associated with more severe disease.
• Subjects:
  Animals Antibodies, Viral Antibody Affinity Antibody Formation Camelus Coronavirus Infections Dispatch Female Humans Kinetics Male Middle East Respiratory Syndrome Coronavirus

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• Source:
  Emerg Infect Dis. 21(12):2186-2189
• Pubmed ID:
  26583829
• Pubmed Central ID:
  PMC4672454
• Document Type:
  Journal Article
• Funding:
  HHSN272201400006C/AI/NIAID NIH HHS/United States
• Place as Subject:
  Republic of Korea
• Location:
  Asia
• Volume:
  21
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:78291e81594056e594d5045205dcf5de528e7ff7fd622533d4b5e08aefb4b85e
• Download URL:
  https://stacks.cdc.gov/view/cdc/36562/cdc_36562_DS1.pdf
• File Type:
  [PDF - 450.83 KB ]