Details:

Alternative Title:
BMC Infect Dis
Publisher's site:
http://dx.doi.org/10.1186/s12879-015-1213-4
Personal Author:
Marcone, Débora Natalia ; Durand, Lizette O. ; Azziz-Baumgartner, Eduardo ; Vidaurreta, Santiago ; Ekstrom, Jorge ; ... More +
Marcone, Débora Natalia ; Durand, Lizette O. ; Azziz-Baumgartner, Eduardo ; Vidaurreta, Santiago ; Ekstrom, Jorge ; Carballal, Guadalupe ; Echavarria, Marcela Less -
Description:
Background

Although information about the incidence of viral respiratory illnesses and their associated cost can help health officials explore the value of interventions, data are limited from middle-income countries.

Methods

During 2008–2010, we conducted a prospective cohort study and followed ~1,800 Argentinian children aged ≤5 years to identify those children who were hospitalized or who sought care at an emergency room with any acute respiratory infection sign or symptom (e.g., rhinorrhea, cough, wheezing, tachypnea, retractions, or cyanosis). Respiratory samples were obtained for respiratory syncytial virus, influenza, parainfluenza, adenovirus, and metapneumovirus testing by immunofluorescence and for rhinovirus by real-time reverse transcription polymerase chain reaction.

Results

The incidence of respiratory syncytial virus (24/1000 children-years), human metapneumovirus (8/1000 children-years), and influenza (8/1000 children-years) illnesses was highest among hospitalized children aged <6 months and decreased among older children. In contrast, the incidence of rhinovirus was highest (12/1000 children-years) among those aged 6–23 months. In the emergency room, the incidence of rhinovirus was 459; respiratory syncytial virus 352; influenza 185; parainfluenza 177; metapneumovirus 130; and adenovirus 73/1,000 children-years. The total cost of hospitalization was a median of US$529 (Interquartile range, US$362–789).

Conclusions

Our findings indicate that respiratory viruses, in particular rhinovirus, respiratory syncytial virus, metapneumovirus, and influenza may be associated with severe illness causing substantial economic burden.


Subject:
[+]
Charges
Children
Hospitalized And Outpatients
Incidence
Influenza
Research Article
Respiratory Syncytial Virus
Rhinovirus

Source:
BMC Infect Dis. 15.
Pubmed ID:
26497393
Pubmed Central ID:
PMC4619328
Document Type:
Journal Article
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:2daf99c4b6b111b73798e0835c92f3175d40a421be77319d305f01b79dffa3ad
File Type:

Supporting Files

• 	12879_2015_1213_Fig1_HTML.gif	gif
  	12879_2015_1213_Fig1_HTML.jpg	jpeg
  	12879_2015_1213_Fig2_HTML.gif	gif
  	12879_2015_1213_Fig2_HTML.jpg	jpeg
  	12879_2015_Article_1213.nxml	txt
  	license.txt	txt

More +