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Developments in understanding acquired immunity and innate susceptibility to norovirus and rotavirus gastroenteritis in children
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2 2015
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Source: Curr Opin Pediatr. 27(1):105-109
[PDF-107.44 KB]
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Alternative Title:Curr Opin Pediatr
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Description:Purpose of review
We discuss recent advances in the understanding of acquired immunity and susceptibility to the two major pediatric enteric viral pathogens, norovirus and rotavirus.
Recent findings
The prominent decline in severe rotavirus gastroenteritis in areas with mature rotavirus vaccination programmes has correspondingly unmasked the significant burden of disease associated with norovirus gastroenteritis among children. As epidemiologists and vaccinologists set their sights on this next vaccine target, we provide an update on norovirus vaccine development.
Summary
This information can potentially be used to tailor both applied and developmental efforts to public health interventions against these important pediatric enteric viral pathogens.
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Pubmed ID:25490691
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Pubmed Central ID:PMC4618547
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Volume:27
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Issue:1
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