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Heartland Virus Neutralizing Antibodies in Vertebrate Wildlife, United States, 2009–2014
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  1. Vertebrate Host Susceptibility to Heartland Virus
    Personal Author:
    Bosco-Lauth, Angela M.; Calvert, Amanda E.; Root, J. Jeffrey; Gidlewski, Tom; Bird, Brian H.; Bowen, Richard A.; Muehlenbachs, Atis; Zaki, Sherif R.; Brault, Aaron C.;
    Published:
    Dec 2016
    Source:
    Emerg Infect Dis. 22(12):2070-2077.
    Description:
    Heartland virus (HRTV) is a recently described phlebovirus initially isolated in 2009 from 2 humans who had leukopenia and thrombocytopenia. Serologic assessment of domestic and wild animal populations near the residence of 1 of these persons showed ...
    File Type:
    Filetype[PDF - 1.50 MB]
  2. Heartland Virus Epidemiology, Vector Association, and Disease Potential
    Personal Author:
    Brault, Aaron C.; Savage, Harry M.; Duggal, Nisha K.; Eisen, Rebecca J.; Staples, J. Erin;
    Published:
    Sep 14 2018
    Source:
    Viruses. 2018; 10(9).
    Description:
    First identified in two Missouri farmers exhibiting low white-blood-cell and platelet counts in 2009, Heartland virus (HRTV) is genetically closely related to severe fever with thrombocytopenia syndrome virus (SFTSV), a tick-borne phlebovirus produci...
    File Type:
    Filetype[PDF - 1.12 MB]
  3. Seroprevalence of Heartland Virus Antibodies in Blood Donors, Northwestern Missouri, USA
    Personal Author:
    Lindsey, Nicole P.; Menitove, Jay E.; Biggerstaff, Brad J.; Turabelidze, George; Parton, Pat; Peck, Kim; Basile, Alison J.; Kosoy, Olga I.; Fischer, Marc; Staples, J. Erin;
    Published:
    Feb 17 2019
    Source:
    Emerg Infect Dis. 25(2):358-360
    Description:
    We estimated the seroprevalence of Heartland virus antibodies to be 0.9% (95% CI 0.4%-4.2%) in a convenience sample of blood donors from northwestern Missouri, USA, where human cases and infected ticks have been identified. Although these findings su...
    File Type:
    Filetype[PDF - 472.89 KB]
  4. Heartland Virus and Hemophagocytic Lymphohistiocytosis in Immunocompromised Patient, Missouri, USA
    Personal Author:
    Carlson, Abigail L.; Pastula, Daniel M.; Lambert, Amy J.; Staples, J. Erin; Muehlenbachs, Atis; Turabelidze, George; Eby, Charles S.; Keller, Jesse; Hess, Brian; Buller, Richard S.; Storch, Gregory A.; Byrnes, Kathleen; Dehner, Louis; Kirmani, Nigar; Kuhlmann, F. Matthew;
    Published:
    May 2018
    Source:
    Emerg Infect Dis. 24(5):893-897.
    Description:
    Heartland virus is a suspected tickborne pathogen in the United States. We describe a case of hemophagocytic lymphohistiocytosis, then death, in an immunosuppressed elderly man in Missouri, USA, who was infected with Heartland virus.
    File Type:
    Filetype[PDF - 1.11 MB]
  5. Neutralizing antibodies against flaviviruses, Babanki virus, and Rift Valley fever virus in Ugandan bats
    Personal Author:
    Kading, Rebekah C.; Kityo, Robert M.; Mossel, Eric C.; Borland, Erin M.; Nakayiki, Teddie; Nalikka, Betty; Nyakarahuka, Luke; Ledermann, Jeremy P.; Panella, Nicholas A.; Gilbert, Amy T.; Crabtree, Mary B.; Peterhans, Julian Kerbis; Towner, Jonathan S.; Amman, Brian R.; Sealy, Tara K.; Nichol, Stuart T.; Powers, Ann M.; Lutwama, Julius J.; Miller, Barry R.;
    Published:
    Feb 21 2018
    Source:
    Infect Ecol Epidemiol. 2018; 8(1).
    Description:
    A number of arboviruses have previously been isolated from naturally-infected East African bats, however the role of bats in arbovirus maintenance is poorly understood. The aim of this study was to investigate the exposure history of Ugandan bats to ...
    File Type:
    Filetype[PDF - 920.05 KB]