Environmental Factors Related to Fungal Wound Contamination after Combat Trauma in Afghanistan, 2009–2011

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Tribble, David R. ; Rodriguez, Carlos J. ; Weintrob, Amy C. ; Shaikh, Faraz ; Aggarwal, Deepak ; Carson, M. Leigh ; Murray, Clinton K. ; Masuoka, Penny
• Corporate Authors:
  on behalf of the Infectious Disease Clinical Research Program Trauma Infectious Disease Outcomes Study Group
• Description:
  During the recent war in Afghanistan (2001-2014), invasive fungal wound infections (IFIs) among US combat casualties were associated with risk factors related to the mechanism and pattern of injury. Although previous studies recognized that IFI patients primarily sustained injuries in southern Afghanistan, environmental data were not examined. We compared environmental conditions of this region with those of an area in eastern Afghanistan that was not associated with observed IFIs after injury. A larger proportion of personnel injured in the south (61%) grew mold from wound cultures than those injured in the east (20%). In a multivariable analysis, the southern location, characterized by lower elevation, warmer temperatures, and greater isothermality, was independently associated with mold contamination of wounds. These environmental characteristics, along with known risk factors related to injury characteristics, may be useful in modeling the risk for IFIs after traumatic injury in other regions.
• Subjects:
  Afghanistan Aspergillus Species Biota Case-Control Studies Environmental Exposure Environmental Factors Related To Fungal Wound Contamination After Combat Trauma In Afghanistan, 2009–2011 Female Fungi Humans Male Military Medicine Military Personnel Mold Mucormycosis Registries Research Risk Factors Trauma Wound Infection Wounds And Injuries Zygomycosis

  More +
• Source:
  Emerg Infect Dis. 21(10):1759-1769
• Pubmed ID:
  26401897
• Pubmed Central ID:
  PMC4593427
• Document Type:
  Journal Article
• Funding:
  Y01 AI005072/AI/NIAID NIH HHS/United States ; Y1-AI-5072/AI/NIAID NIH HHS/United States
• Volume:
  21
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:29f318d045a9341c62b45799ea4012f0dadb8dd6bd83f426e88dd4a2908a53f8
• Download URL:
  https://stacks.cdc.gov/view/cdc/34703/cdc_34703_DS1.pdf
• File Type:
  [PDF - 657.51 KB ]